Genetic Mutations
161 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Taking a Systems Biology Approach to Find a New Pancreatic Cancer Target
Dr. Andrea Califano is using systems biology and cell regulators to find new targets in the search for ways to stop pancreatic cancer cells.
“Radical Collaboration” to Find Cures for the Deadliest Cancers
Break Through Cancer was founded to promote collaboration between major research institutions, in order to develop cures for the deadliest cancers.
An Interview with Dr. Tyler Jacks
Dr. Tyler Jacks is one of the leading pancreatic cancer researchers. Read what he has to say about KRAS, organoids, and running a lab in a pandemic.
Surprising Clinical Trial Results in Pancreatic and Rectal Cancer
Let’s Win Scientific Advisory Board Chair Dr. Allyson Ocean explains the surprising clinical trial results in pancreatic and rectal cancers.
Understanding How Super-Enhancers Rev Up Pancreatic Cancer Growth
Researcher Ronald Evans, Ph.D., and his team at the Salk Institute are focusing on how super-enhancers stimulate pancreatic cancer growth.
Testing an Approved Drug for a Specific Mutation
Researchers are testing a drug combination for melanoma in pancreatic cancer patients with a BRAF genetic mutation.
Is Pancreatic Cancer Different in Black Patients?
Pancreatic cancer occurs at a higher rate in Black patients. Dr. Howard Crawford leads a study looking at the cancer biology for differences.
New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors
A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.
Genetic Testing Guided My Treatment Plan
Ryan Dwars already knew there was pancreatic cancer in his family so when he was diagnosed he asked for genetic testing right away.
Who Should Be Screened For Pancreatic Cancer
Who should be screened for pancreatic cancer? Dr. Allyson Ocean explains how genetic mutations and family history factor into screening.
Cherishing the Simple Things
Elizabeth O’Connor has a PALB2 genetic mutation so her stage IV pancreatic cancer has responded to immunotherapy.
Don’t Let Doctors Tell You Nothing’s Wrong
After a long road to diagnosis Brandon Stone learned he has a BRCA2 genetic mutation that impacts his treatment.
(Currently) Incurable, (Continuously) Fighting
Katie DeCarlo is continuously fighting her PNET. She is determined to try and will continue to try as many types of treatment as possible
Decoding the Differences between At-Home and Medical Genetic Testing
Genetic counselors Jill Stopfer and Heather Hampel explain the differences between at-home and medical genetic testing, including precision and knowledge.