Genetic Mutations

159 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Research
August 9, 2023 • 5 Min

“Radical Collaboration” to Find Cures for the Deadliest Cancers

Break Through Cancer was founded to promote collaboration between major research institutions, in order to develop cures for the deadliest cancers.

Research
June 17, 2022 • 3 Min

New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors

A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.

Diabetes
June 29, 2021 • 6 Min

Will New-Onset Diabetes Provide a Way to Detect Pancreatic Cancer Earlier?

Dr. Anirban Maitra, Dr. Suresh Chari, and others are looking at the relationship between new-onset diabetes and pancreatic cancer.

Research
January 27, 2021 • 6 Min

A Look at MEK and Autophagy Inhibition

Dr. Conan Kinsey looks at the MEK pathway as way to make immunotherapy more effective for pancreatic cancer patients.

Research
February 28, 2019 • 5 Min

MRI-Guided Radiation: A New Option for Pancreatic Cancer Treatment

Dr. Parag Parikh and others are using MRI-guided radiation to provide precision radiation treatment for pancreatic cancer.

Research
January 16, 2018 • 3 Min

Neoantigens Provide New Hope for Pancreatic Cancer Treatments

Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.

Research
March 11, 2022 • 2 Min

Testing an Approved Drug for a Specific Mutation

Researchers are testing a drug combination for melanoma in pancreatic cancer patients with a BRAF genetic mutation.

Research
May 15, 2023 • 5 Min

Is Pancreatic Cancer Different in Black Patients?

Pancreatic cancer occurs at a higher rate in Black patients. Dr. Howard Crawford leads a study looking at the cancer biology for differences.

Managing Your Care
February 18, 2020 • 8 Min

Decoding the Differences between At-Home and Medical Genetic Testing

Genetic counselors Jill Stopfer and Heather Hampel explain the differences between at-home and medical genetic testing, including precision and knowledge.

Screening and Early Detection
April 14, 2023 • 5 Min

Who Should Be Screened For Pancreatic Cancer

Who should be screened for pancreatic cancer? Dr. Allyson Ocean explains how genetic mutations and family history factor into screening.

Survivor Stories
October 9, 2024 • 6 Min

Genetic Testing Guided My Treatment Plan

Ryan Dwars already knew there was pancreatic cancer in his family so when he was diagnosed he asked for genetic testing right away.

The Importance of Genetic Testing
December 1, 2017 • 6 Min

Before You Leap: Genetic Testing for Pancreatic Cancer

Genetic counselor Megan Frone outlines the advantages of genetic testing when there is a family history of pancreatic cancer.

Treatments
December 21, 2020 • 5 Min

This Versus That: Words to Know

Confused about some of the similar-sounding terms you are hearing during pancreatic cancer treatment? Our list of words to know can help.

Page
July 19, 2023 • 5 Min

Family History

Does it Run in My Family? The connection between your family’s medical history and pancreatic cancer As you may already know, cancer can run in families. In fact, people carrying certain genetic mutations have an increased risk of getting cancers including breast, colon, prostate, ovarian, and pancreatic cancer. All told, researchers estimate that known genetic […]

Symptoms
February 9, 2022 • 5 Min

Understanding Who Is at High Risk for Pancreatic Cancer

Who is high-risk for pancreatic cancer? Oncologist Dr. Matthew Yurgelun explains high-risk populations and what steps to take if you meet the criteria.