Genetic Mutations

161 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Research
January 9, 2019 • 6 Min

Pancreatic Cancer: 2018 Highlights And Looking Forward to 2019

Dr. Allyson Ocean leads an overview of the new treatments and protocol from 2018 as well as what are the next steps in treatment for 2019.

Research
September 15, 2025 • 5 Min

PLATINUM Clinical Trial Actively Recruiting

The PLATINUM clinical trial, for patients with BRCA and PALB2 mutations, seeks participants. Dr. Andrew Ko outlines the trial.

Research
October 12, 2017 • 5 Min

Tumor Genetics Research Brings Some Answers for Families at High Risk

Professor Gloria Peterson of the Mayo Clinic is working on tumor genetics to help make early detection of pancreatic cancer a reality.

Research
October 12, 2023 • 8 Min

Pancreatic Cancer Research Builds Upon Strengths

The September 2023 AACR Special Conference on Pancreatic Cancer focused on the latest research in KRAS, chemotherapy, and cachexia, among other topics.

Research
December 23, 2019 • 5 Min

Looking Back at the Year in Research: 2019

Research highlights of 2019 include: approval of a PARP inhibitor, artificial intelligence to diagnose pancreatic cysts, and updated radiation guidelines.

Research
October 29, 2025 • 6 Min

The Latest Research from the 2025 AACR Special Conference

Highlights from the 2025 AACR Special Conference on pancreatic cancer research include updates on drugs that work on KRAS, AI and early detection, and biomarkers.

Research
October 19, 2018 • 4 Min

Which Is the Best Screening Method for Pancreatic Cancer?

Dr. Aimee Lucas outlines the pros and cons of various screening methods that can be used for pancreatic cancer, and who should be using them.

Research
February 4, 2019 • 5 Min

Genetic Testing for All Pancreatic Cancer Patients

A study by Dr. Gloria Petersen’s research team has led to an official recommendation that all pancreatic cancer patients get genetic testing.

Research
December 5, 2017 • 5 Min

The ABCs of Genetic Testing

There are a number of different genetic mutations that can cause familial pancreatic cancer. This article explains some of the most common ones.

Research
February 9, 2023 • 5 Min

PRECEDE Trial Sets Survival Rate Goal

Dr. Raymond Wadlow explains how earlier detection of high-risk people is key the PRECEDE trial’s goal to increase pancreatic cancer survival rates.

Research
January 5, 2026 • 7 Min

Rewinding 2025: A Year in Pancreatic Cancer Research

We take a look back at the research developments in 2025: KRAS, earlier detection and screening, vaccines, and clinical trials.

Research
April 26, 2021 • 5 Min

Improving Access to Genetic Testing and Counseling

Dr. Angela Bradbury is leading a study on access to genetic testing and genetic counseling, including a telehealth option.

Research
February 26, 2020 • 6 Min

Exploiting DNA Mutations For Pancreatic Cancer Treatment

Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.

Research
January 12, 2022 • 5 Min

New Study Aims to Reduce Recurrence Risk for Select Patients

Dr. Kim A. Reiss is leading a study of the PARP inhibitor olaparib to delay or prevent a recurrence of surgically removed pancreatic cancer.

Screening and Early Detection
October 21, 2016 • 5 Min

Can a Pancreatic Cancer Screening Test Become a Reality?

Dr. Felice Schnoll-Sussman discusses screening options for pancreatic cancer and criteria for people who might want to get screened.