Trials for Locally Advanced Disease - Clinical Trials

A latex-gloved hand doing close lab work

Targeting Cancer-Associated Wasting With Experimental Immunotherapy

Wasting, or cachexia, is the focus of a clinical trial testing a cachexia immunotherapy treatment combined with standard pancreatic cancer treatment.

A human epithelial cell (DNA in blue) with increased numbers of centrosomes (green) amid a sea of normal cells.

Combining Immunotherapy and Targeted Therapy for Pancreatic Cancer

Researchers are combining immunotherapy and targeted therapy in a clinical trial for pancreatic cancer patients on platinum-based chemotherapy.

black disc in motion against a yellow background

Electric Fields to Enhance Pancreatic Cancer Chemotherapy

A clinical trial uses electric fields to help slow the growth of tumor cells, In a clinical trial for pancreatic cancer patients.

Grayscale image of round lab containers with dark agar medium arranged in rows.

Finding a Safe Dose of a New Drug for Some Types of Solid Tumors

LMB-100 is a lab-created protein that targets mesothelin. It is being tested against pancreatic cancer and other solid tumors in a clinical trial.

Radiotherapy Implant plus Standard Chemotherapy

The OncoSil radiotherapy implant device is being tested on pancreatic cancer in a clinical trial that combines it with standard chemotherapy.

orange colored clear vitamin D pills in a circle against an orange background

A New Combination Chemotherapy Before Surgery

A new clinical trial adds vitamin D to standard of care chemotherapy before surgery, to make pancreatic cancer tumors more removable.

Tiny beams of X-ray radiation are generated using an array of carbon nanotube X-ray sources to deliver tumor-killing radiation, while preserving normal tissue; this micrograph shows a 250 micron wide section of tissue damage.

Finding the Best Dose of Radiation and an Experimental Drug

A clinical trial looks for the best dose of an experimental drug to combat the mouth sores that are a side effect of radiation treatment.

a rack of beakers with red, blue, and green liquids

Noninvasive Surgery and a New Drug to Stop Pancreatic Tumors

A clinical trial combines irreversible electroporation (IRE) and immunotherapy to see if the duo is effective against locally advanced pancreatic cancer.

Abstract image of roundish shapes packed together, in shades of yellow to black colors

Chemotherapy, Immunotherapy, and Radiation for Locally Advanced Pancreatic Cancer

A clinical trial is testing chemotherapy that enhances the action of two immunotherapy drugs and SBRT to stop locally advanced pancreatic cancer.

Microscope slide of the pancreas, with the some structures in purple and some in pink

More Effective Focused Radiation Therapy and Chemotherapy for Locally Advanced Pancreatic Cancer

A clinical trial tests whether adding Zometa makes chemotherapy and stereotactic body radiation therapy (SBRT) more effective against pancreatic cancer.