Clinical Trials

117 Articles

Hepatocyte spheroid, imaged with Lightsheet Z.1 in bright colors against a dark background
Research
January 19, 2022 • 2 Min

Modifying the Tumor Microenvironment to Make Treatment More Effective

Researchers are testing a new drug that better-allows chemotherapy to penetrate the tumor microenvironment of pancreatic cancer.

Dr. Elizabeth Jaffee
Research
November 4, 2021 • 5 Min

New Clinical Accelerator Initiative Shortens Time from Bench to Clinic

Dr. Elizabeth Jaffee explains the importance of Lustgarten’s Clinical Accelerator Initiative to speed up the time from bench to trial.

model of DNA structure
Research
September 7, 2021 • 2 Min

Testing a Combination for Metastatic Pancreatic Cancer

A clinical trial tests an investigational drug, immunotherapy, and radiation in combination against advanced pancreatic cancer.

Dr. Philip Philip
Research
August 19, 2021 • 5 Min

Large Phase III Global Trial Targets Cancer Metabolism

Dr. Philip Philip focuses on disrupting cancer cell metabolism with devimistat, now in a phase III global clinical trial.

Research
June 21, 2021 • 3 Min

CRISPR-Engineered Immunotherapy for Metastatic GI Tract Cancers

CRISPR technology is used as part of an immunotherapy clinical trial for metastatic pancreatic cancer and other GI cancers.

Dr. Tanios Bekaii-Saab
Research
June 3, 2021 • 4 Min

Disappointing Results of a Phase II Trial Using Angiogenesis Inhibitor

Dr. Tanios Bekaii-Saab reports on the disappointing results of a trial combining an angiogenesis inhibitor and mFOLFIRINOX.

Dr. Matthew Katz
Research
April 6, 2021 • 5 Min

New Data Support Preoperative Chemoradiation Regimen for Borderline Resectable Pancreatic Cancer

Should patients get chemotherapy or chemoradiation before surgery? Dr. Matthew Katz provides an update on the Alliance study.

Research
April 5, 2021 • 2 Min

Adaptive Pre-Surgery Therapy for Patients with Localized Pancreatic Cancer

Will a flexible approach to neoadjuvant treatment work better for pancreatic cancer patients with tumors that can be removed surgically?

DNA scan of rainbow colors on a royal blue background
Research
January 5, 2021 • 1 Min

Comparing Effectiveness of Chemotherapy Before and After Surgery

Is chemotherapy before and after pancreatic cancer surgery more effective than just chemotherapy after surgery?

Dark leafy greens in a bowl
Research
December 8, 2020 • 1 Min

Medical Diet Study for Pancreatic Cancer Patients

Researchers are looking at the role of one particular nutrient in a diet study for pancreatic cancer patients.

Dr. Vincent Picozzi
Research
November 11, 2020 • 5 Min

Multi-Site Precision Promise Study Opens

Dr. Vincent Picozzi explains how Precision Promise clinical trial will use a personalized approach for pancreatic cancer patients.

colored lights in 1/4 of a circle
Research
November 6, 2020 • 2 Min

An Expanded Access Trial for Cancer Patients with Specific Mutations

An investigational drug is being used in an expanded access trial for advanced pancreatic and other cancer patients with specific genetic changes.

black and white image of laboratory equipment
Research
October 16, 2020 • 2 Min

Attacking Cancer’s Key Mechanisms to Treat Metastatic Pancreatic Cancer

A clinical trial for patients with metastatic pancreatic cancer uses the new drug SM-88 in combination with other agents, to attack the tumor metabolism.

microscope image of zebrafish scales in blues and greens
Research
September 22, 2020 • 2 Min

Safety and Effectiveness of a New Drug for Advanced Pancreatic Cancer

Researchers are testing dose safety and effectiveness of a new drug for pancreatic cancer, in combination with gemcitabine.

white 3-d hexagons on a black background
Research
August 26, 2020 • 1 Min

Testing a New Approach to Treating Advanced Pancreatic Cancer

Scientists are testing a new drug that is an antagonist of stress hormone receptors, in combination with nab-paclitaxel, for advanced pancreatic cancer.