Genetic Mutations

391 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Survivor Stories
April 2, 2016 • 2 Min

A 10-Year Survivor’s Story

Howard Ebert, a 10-year survivor of pancreatic cancer, describes his treatment. He underwent surgery and then chemotherapy and radiation.

Survivor Stories
October 17, 2017 • 3 Min

Early Detection Makes All the Difference

Carolynn Kiel lost her mother and sister to pancreatic cancer. Regular screening allowed early detection of her pancreatic cancer.

Survivor Stories
May 5, 2022 • 3 Min

My Journey with Pancreatic Cancer

Dr. Robert Wagar lost both parents to pancreatic cancer. When his wife found an article about a surveillance study he had an MRI, which found a lesion.

Survivor Stories
January 10, 2023 • 4 Min

Taking Chances to Beat Pancreatic Cancer

With a family history of pancreatic cancer, Jay Bozick discovered he carries the BRCA2 mutation, which directed his treatment.

Survivor Stories
December 12, 2024 • 3 Min

Gathering Information for the Right Treatment

Staci and Rich Grodin applied their medical information research skills when Rich was diagnosed with pancreatic cancer.

Research
January 9, 2025 • 5 Min

A Look Back at Research in 2024

Research in 2024 focused on personally tailored treatments, countering the most difficult effects of pancreatic cancer, and clinical trials.

Treatments
December 27, 2019 • 5 Min

Chemotherapy: A Key Player in the Battle Against Pancreatic Cancer

Dr. Gabriela Chiorean walks us through the different types of chemotherapy treatments for pancreatic cancer and how they work.

Survivor Stories
August 2, 2016 • 3 Min

Currently in the Fight, at Memorial Sloan Kettering Cancer Center

A woman’s treatment for non-operable pancreatic cancer at Memorial Sloan Kettering includes FOLFIRINOX and stereotactic body radiation therapy.

Research
April 14, 2022 • 5 Min

KRYSTAL-1 Trial Shows Promising Activity in Pancreas and Other GI Cancers

Dr. Tanios Bekaii-Saab reports promising results of the KRYSTAL-1 trial, which targets a KRAS mutation common to pancreatic cancer.

Research
February 14, 2018 • 4 Min

A Simple Blood Test for Early Detection of Eight Cancers Shows Promise

Dr. Anne Marie Lennon explains the CancerSEEK blood test, a liquid biopsy in clinical trials for early detection of eight cancers, including pancreatic.

Survivor Stories
January 22, 2020 • 1 Min

Identify Your Risk Early

Long-term survivor Scott Nelson was diagnosed with pancreatic cancer, so older brother Steve joined a screening study, which caught his cancer at its earliest stages.

Survivor Stories
July 11, 2023 • 4 Min

Genetic Profiling Leads to a Clinical Trial

With treatment not working and nothing to lose, Cathleen Janosko did her research and got help finding a clinical trial to match her tumor’s mutation.

Survivor Stories
November 16, 2020 • 4 Min

Practicing Gratitude Every Day

The best thing Chris Joseph ever did was change oncologists. His new doctor did genetic testing on Chris’s tumor, for better treatment.

Webinars
April 30, 2021 • 1 Min

Find Treatment Options

In Find Treatment Options, oncologists and genetic counselors discuss treatments and the importance of genetic testing.

Research
February 13, 2020 • 5 Min

Clinical Trial For OncoTreat Being Developed

Researcher Kenneth Olive is developing OncoTreat, a method matches a patient’s tumor to the most effective drugs for their pancreatic cancer.