Genetic Mutations

359 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Survivor Stories
December 27, 2023 • 7 Min

A Long Journey That Began With Pancreatitis

Paul Suntup’s diagnosis of acinar cell pancreatic cancer was just the start of a long treatment journey, but he’s still here.

Survivor Stories
December 14, 2016 • 5 Min

Finding a Treatment Geared to My Cancer

Samuel Chi describes his search for a pancreatic cancer treatment that allows him to live comfortably and reduce his tumor so he can have surgery.

Research
July 11, 2019 • 2 Min

Immunotherapy to Attack a Common Pancreatic Cancer Mutation

Researchers are testing a type of immunotherapy to attack a variant of the KRAS mutation; KRAS mutations occur in almost all pancreatic cancers.

Research
January 13, 2021 • 5 Min

Finding More Targets for Pancreatic Cancer Treatment

Dr. Noelle LoConte discusses a clinical trial for cancer patients, including pancreatic cancer patients, that have an NRG1 gene fusion.

Research
January 27, 2023 • 6 Min

Research Updates from ASCO GI 2023

Read the latest clinical trial and research updates from the 2023 ASCO GI meeting, including a review of genetic testing uptake.

Research
October 13, 2020 • 8 Min

An Interview with Dr. Tyler Jacks

Dr. Tyler Jacks is one of the leading pancreatic cancer researchers. Read what he has to say about KRAS, organoids, and running a lab in a pandemic.

Research
October 1, 2021 • 7 Min

The American Association for Cancer Research (AACR) Virtual Special Conference: Pancreatic Cancer Day One

Let’s Win and the Lustgarten Foundation present highlights of Day One of the AACR Virtual Special Conference on Pancreatic Cancer.

Survivor Stories
April 2, 2016 • 2 Min

A 10-Year Survivor’s Story

Howard Ebert, a 10-year survivor of pancreatic cancer, describes his treatment. He underwent surgery and then chemotherapy and radiation.

Survivor Stories
October 17, 2017 • 3 Min

Early Detection Makes All the Difference

Carolynn Kiel lost her mother and sister to pancreatic cancer. Regular screening allowed early detection of her pancreatic cancer.

Survivor Stories
May 5, 2022 • 3 Min

My Journey with Pancreatic Cancer

Dr. Robert Wagar lost both parents to pancreatic cancer. When his wife found an article about a surveillance study he had an MRI, which found a lesion.

Survivor Stories
January 10, 2023 • 4 Min

Taking Chances to Beat Pancreatic Cancer

With a family history of pancreatic cancer, Jay Bozick discovered he carries the BRCA2 mutation, which directed his treatment.

Treatments
December 27, 2019 • 5 Min

Chemotherapy: A Key Player in the Battle Against Pancreatic Cancer

Dr. Gabriela Chiorean walks us through the different types of chemotherapy treatments for pancreatic cancer and how they work. Join Let’s Win PC in our fight.

Survivor Stories
August 2, 2016 • 3 Min

Currently in the Fight, at Memorial Sloan Kettering Cancer Center

A woman’s treatment for non-operable pancreatic cancer at Memorial Sloan Kettering includes FOLFIRINOX and stereotactic body radiation therapy.

Research
April 14, 2022 • 5 Min

KRYSTAL-1 Trial Shows Promising Activity in Pancreas and Other GI Cancers

Dr. Tanios Bekaii-Saab reports promising results of the KRYSTAL-1 trial, which targets a KRAS mutation common to pancreatic cancer.

Research
February 14, 2018 • 4 Min

A Simple Blood Test for Early Detection of Eight Cancers Shows Promise

Dr. Anne Marie Lennon explains the CancerSEEK blood test, a liquid biopsy in clinical trials for early detection of eight cancers, including pancreatic.