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Comparing a Standard Chemotherapy With and Without a PARP Inhibitor
A clinical trial compares standard chemotherapy with and without the addition of a PARP inihibitor, for patients whose pancreatic cancer is spreading again.
If Something Feels Wrong, Insist on Testing
Kristin Sine wanted an answer to her mysterious pain, but she had to insist on testing to find out she had a pancreatic neuroendocrine tumor.
Radiation Therapy to Fight Pancreatic Cancer
Dr. Smith Apisarnthanarax, a radiation oncologist, details the different types of radiation therapy given to pancreatic cancer patients.
Genetic Testing and Molecular Profiling Can Guide Treatment
Watch our webinar on Genetic Testing and Molecular Profiling to learn from experts and patients why this is so important.
Steely Strength to Keep Going
Long-term survivor Davi D’Agostino discovered she carries the BRCA2 mutation, which changed her treatment plan to targeted therapy.
Pancreatic Cancer Treatment During the COVID-19 Pandemic
During the March 2020 PancChat, pancreatic cancer experts discussed treatment during the COVID-19 pandemic, along with other important issues for patients.
KRYSTAL-1 Trial Shows Promising Activity in Pancreas and Other GI Cancers
Dr. Tanios Bekaii-Saab reports promising results of the KRYSTAL-1 trial, which targets a KRAS mutation common to pancreatic cancer.
Claudin May Be the Next Big Target in Pancreatic Cancer Treatment
Dr. Wungki Park leads a trial that uses a monoclonal antibody to target a protein that is common in pancreatic cancer.
A Look at MEK and Autophagy Inhibition
Dr. Conan Kinsey looks at the MEK pathway as way to make immunotherapy more effective for pancreatic cancer patients.
Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer
Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.
MRI-Guided Radiation: A New Option for Pancreatic Cancer Treatment
Dr. Parag Parikh and others are using MRI-guided radiation to provide precision radiation treatment for pancreatic cancer.
Immunology Researchers Solve a Mystery of Metastasis
Physician and researcher Douglas Fearon and his lab have a possible explanation for how cancer cells metastasize, and the role surgery may play in this process.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Overcoming Challenges to Vaccine Immunotherapy
Dr. Elizabeth Jaffee explains the challenges facing the scientists developing vaccine-based immunotherapy for pancreatic cancer.