drug combination
422 articles
Targeting the Undruggable KRAS Protein
Dr. Shubham Pant is focusing his research on effective treatments for the KRAS mutation, found in 90% of pancreatic cancers.
Challenge Grant Recipients Moving Forward
The Pancreatic Cancer Collective awarded four teams a second round of New Therapies Challenge Grants, to further develop new pancreatic cancer treatment.
Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer
A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.
Comparing the Effectiveness of Vaccine Therapy With or Without Additional Immunotherapy
Can the immunotherapy combination of cancer vaccines and a checkpoint blockade drug work against metastatic pancreatic cancer?
Research and Other Highlights from the 2023 AACR Annual Meeting
The 2023 AACR meeting focused on the latest research into KRAS, other immunotherapy approaches, and honored Dr. Elizabeth Jaffee.
The Importance of Clinical Trials
Judith Goldring outlines her treatments for pancreatic cancer using a series of clinical trials, as her cancer progresses.
Chemoradiation Before Tumor Removal to Lessen Possible Post-Surgical Disease
A clinical trial examines the effectiveness of presurgical chemotherapy and radiation in making cancer-free margins after tumor removal.
New Cancer Stem Cell Pathway Drug May Change Standard of Care
Dr. Tanios Bekaii-Saab is testing a new drug that works on pancreatic cancer stem cells to make chemotherapy more effective.
BRCA’s Role in Pancreatic Cancer Investigated
The relationship between BRCA and pancreatic cancer, and how that affects treatment, is the focus of clinical trials looking at PARP inhibitors.
Presurgical Treatment for Pancreatic Cancer That Is Removable
A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.
Testing the Effect of a Malaria Drug on Standard Treatment
A clinical trial tests whether a malaria drug can make standard chemotherapy for advanced pancreatic cancer more effective.
Predicting Effective Therapy in Pancreatic Cancer
Dr. Kenneth Yu is leading a clinical trial that looks at a pancreatic cancer patient’s pharmacogenomic profile, to see which chemotherapy works better.
Immunotherapy to Help Shrink Pancreatic Tumors for Surgery
Researchers are looking at adding checkpoint drugs–a type of immunotherapy–to standard chemoradiation to shrink pancreatic cancer for surgery.
Testing a New Approach to Treating Advanced Pancreatic Cancer
Scientists are testing a new drug that is an antagonist of stress hormone receptors, in combination with nab-paclitaxel, for advanced pancreatic cancer.
COMBATing Pancreatic Cancer
Dr. Manuel Hidalgo explains the COMBAT trial, which combines immunotherapy, a checkpoint inhibitor, and chemotherapy to attack pancreatic cancer.