Immunotherapy
192 articles
Putting the Immune System on the Offensive
A discussion of immunology in cancer treatment, focusing on the work of Elizabeth Jaffe, M.D., and her cancer vaccine and checkpoint inhibitors.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Research and Other Highlights from the 2023 AACR Annual Meeting
The 2023 AACR meeting focused on the latest research into KRAS, other immunotherapy approaches, and honored Dr. Elizabeth Jaffee.
Phase II mRNA Vaccine Trial Opens
The mRNA vaccine phase II clinical trial, led by Dr. Vinod Balachandran, has opened at Memorial Sloan Kettering, with other locations soon to come.
Claudin May Be the Next Big Target in Pancreatic Cancer Treatment
Dr. Wungki Park leads a trial that uses a monoclonal antibody to target a protein that is common in pancreatic cancer.
Taking a Look At FAK Inhibitors
Dr. Conan Kinsey is looking at how FAK inhibitors can make immunotherapy more effective in combination with chemotherapy.
2024 AACR Meeting Update
Some of the highlights of the latest pancreatic cancer research from the 2024 AACR meeting include the mRNA vaccine, and a liquid biopsy.
CAR T Cell Trial Targets Mesothelin
In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.
A Vaccine To Boost Immune Response to Pancreatic Cancer
Researchers are testing whether a vaccine can heighten the body’s immune response to pancreatic cancer after surgical removal of the tumor.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Research Updates from ASCO GI 2023
Read the latest clinical trial and research updates from the 2023 ASCO GI meeting, including a review of genetic testing uptake.
Brain Cancer Vaccine for Metastatic PNET
Researchers are testing a vaccine for PNET that targets a protein that is very abundant in many neuroendocrine tumors.
mRNA Pancreatic Cancer Vaccine Trial Heading for Phase II
Dr. Vinod Balachandran provides the latest data on the mRNA pancreatic cancer vaccine, now headed to a phase II clinical trial.
ASCO 2023: Pancreatic Cancer Research Update
The pancreatic cancer research reports from ASCO 2023 focused on different chemotherapy combinations, including immunotherapy.
Taking Nothing For Granted
After Whipple surgery and chemoradiation, Susan Zbacnik had molecular profiling, genetic testing, and joined an Immunotherapy clinical trial.