Immunotherapy
198 articles
Progress and Promise—Research in 2023
What advances were made in 2023 for pancreatic cancer treatments? Where is research headed in the coming year?
A New Vaccine for Advanced Pancreatic Cancer
An mRNA vaccine that works against KRAS mutations is being tested with and without immunotherapy for advanced or metastatic pancreatic cancer.
Putting the Immune System on the Offensive
A discussion of immunology in cancer treatment, focusing on the work of Elizabeth Jaffe, M.D., and her cancer vaccine and checkpoint inhibitors.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Research and Other Highlights from the 2023 AACR Annual Meeting
The 2023 AACR meeting focused on the latest research into KRAS, other immunotherapy approaches, and honored Dr. Elizabeth Jaffee.
Phase II mRNA Vaccine Trial Opens
The mRNA vaccine phase II clinical trial, led by Dr. Vinod Balachandran, has opened at Memorial Sloan Kettering, with other locations soon to come.
Claudin May Be the Next Big Target in Pancreatic Cancer Treatment
Dr. Wungki Park leads a trial that uses a monoclonal antibody to target a protein that is common in pancreatic cancer.
Taking a Look At FAK Inhibitors
Dr. Conan Kinsey is looking at how FAK inhibitors can make immunotherapy more effective in combination with chemotherapy.
2024 AACR Meeting Update
Some of the highlights of the latest pancreatic cancer research from the 2024 AACR meeting include the mRNA vaccine, and a liquid biopsy.
AACR Special Conference Highlights Advances in Pancreatic Cancer Research
Here are some of the most interesting highlights from the 2024 AACR Special Conference on Pancreatic Cancer Research.
CAR T Cell Trial Targets Mesothelin
In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.
A Vaccine To Boost Immune Response to Pancreatic Cancer
Researchers are testing whether a vaccine can heighten the body’s immune response to pancreatic cancer after surgical removal of the tumor.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Research Updates from ASCO GI 2023
Read the latest clinical trial and research updates from the 2023 ASCO GI meeting, including a review of genetic testing uptake.
Brain Cancer Vaccine for Metastatic PNET
Researchers are testing a vaccine for PNET that targets a protein that is very abundant in many neuroendocrine tumors.