drug combinations

355 articles

Photo of pill capsules with blue and beige ones in focus in the front, and out of focus pills in brown, pink and brown, and blue and beige in the background
Research
August 17, 2017 • 2 Min

Presurgical Treatment for Pancreatic Cancer That Is Removable

A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.

Julie Sutcliffe in her lab
Research
October 4, 2019 • 5 Min

Harnessing the Power of Radionuclide Therapy

Julie Sutcliffe is working with targeted radionuclide therapy to go after pancreatic cancer cells that have spread beyond the pancreas.

Illustration of the DNA double helix in red, blue, purple, yellow, orange, and green. There is a main spiral in the center and two faded spirals on the left and right.
Research
August 10, 2016 • 2 Min

Using a Colon Cancer Drug to Treat Advanced Pancreatic Cancer

A clinical trial tests the effectiveness of an approved colon cancer drug against advanced pancreatic neuroendocrine cancer.

abstract image of stem cells with a large area of red, interspersed with blue, and bright green areas at the bottom of the image
Research
June 15, 2017 • 2 Min

Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer

A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.

clear test tubes with black caps and wavy lines on them sit upright in a solid metal rack, with red, white, and blue light shined on them
Research
October 9, 2017 • 1 Min

Investigating a Drug Used for Other Cancers

In a clinical trial, researchers are adding the drug decitabine to gemcitabine, for patients with advanced cancer that is not responding to treatment.

microscope image of the structure of blood vessel endothelium with the proteins that hold the shapes in red
Research
June 14, 2019 • 2 Min

Testing a New Drug to Attack Pancreatic Tumor Blood Vessels

A clinical trial is testing a new drug combination that damages the tumor blood vessels and allows chemotherapy drugs to enter the tumor.

microscope image of zebrafish scales in blues and greens
Research
September 22, 2020 • 2 Min

Safety and Effectiveness of a New Drug for Advanced Pancreatic Cancer

Researchers are testing dose safety and effectiveness of a new drug for pancreatic cancer, in combination with gemcitabine.

bright colored yellow, red, and green dots in square patterns on a black background
Research
June 17, 2022 • 3 Min

New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors

A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.

Radiation Whole Abdomen
Research
September 21, 2023 • 2 Min

Testing the Addition of a New Drug to Radiation Therapy for Localized Pancreatic Cancer

In combination with radiation treatment, researchers are testing a new drug that causes DNA damage to make that treatment more effective.

Illustration of the twisting spirals of two DNA double helices in royal blue and purple on a turquoise colored background
Research
October 18, 2016 • 2 Min

A New Drug Combination to Control Advanced Pancreatic Cancer

A clinical trial for pancreatic cancer patients with the BRCA mutation tests the effectiveness of standard treatment plus a PARP inhibitor.

Grayscale image of round lab containers with dark agar medium arranged in rows.
Research
October 16, 2018 • 2 Min

Finding a Safe Dose of a New Drug for Some Types of Solid Tumors

LMB-100 is a lab-created protein that targets mesothelin. It is being tested against pancreatic cancer and other solid tumors in a clinical trial.

lab cylinders, beakers, glass bottles upside down on a drying rack
Research
April 17, 2016 • 3 Min

Drug Onivyde Gives New Hope to Patients with Advanced Pancreatic Cancer

Onivyde (injectable irinotecan), combined with fluorouracil and leucovorin, has been approved as a second-line treatment for advanced pancreatic cancer.

Very high magnification of a pancreatic neuroendocrine tumor in a microscope
Research
April 10, 2018 • 2 Min

Testing a New Drug on Advanced Pancreatic Neuroendocrine Tumors

In a clinical trial, the new drug sapanisertib is being tested for its effectiveness against pancreatic neuroendocrine tumors (PNETs).

red prescription pills on a white background
Research
August 12, 2022 • 2 Min

Hypertension Drug as Part of First-Line Treatment for Unresectable Pancreatic Cancer

Researchers are testing if the addition of a hypertension drug to standard treatment will be more effective for advanced pancreatic cancer.

Microscope image of four pancreatic cells with pinkish edges and green centers, against a dark background
Research
October 10, 2016 • 2 Min

A Novel Combination to Slow Pancreas Tumors that Cannot Be Surgically Removed

Can a combination of standard drugs, a PARP inhibitor, and intensity modulated radiation therapy to slow pancreatic tumor growth?