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Cancer Cells’ “Self Eating” May Be New Drug Target

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Cancer cells use a bizarre strategy to reproduce in a tumor’s low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising new target for pancreatic cancer therapies.

Why would a cancer cell want to destroy its own functioning mitochondria? “It may seem pretty counterintuitive,” admits M.D.-Ph.D. student Brinda Alagesan, a member of Dr. David Tuveson’s lab at CSHL. Read more . . . 


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