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Targeting HGF/c-MET Axis in Pancreatic Cancer

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The review by Pothula et al. well describes and comments on the relevant role of HGF/MET in pancreatic cancers; the main point of the cross talk between tumor and stroma, mediated by this ligand/receptor pair, is extensively discussed.

As a general comment, the review should not be contain an overview on all HGF/c-MET roles, but  it would be better if the authors emphasize the relevance of these activities specifically in relation to particular features of Pancreatic Cancer (PC). Read more . . . 

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