As a general comment, the review should not be contain an overview on all HGF/c-MET roles, but it would be better if the authors emphasize the relevance of these activities specifically in relation to particular features of Pancreatic Cancer (PC). Read more . . .
The review by Pothula et al. well describes and comments on the relevant role of HGF/MET in pancreatic cancers; the main point of the cross talk between tumor and stroma, mediated by this ligand/receptor pair, is extensively discussed.