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Exploring the Role of Long Non-Coding RNA in Cancer Development

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Long RNA molecules carrying DNA codes that don’t get translated into proteins have long been a mystery of the human genome. Now, scientists at Duke-NUS Medical School have found a way to systematically investigate their functions and discovered some could play a role in pancreatic cancer.

Their findings, published in the journal Genome Medicine, highlight the importance of investigating long non-coding RNAs (lncRNAs) in living organisms. RNA had long been considered an intermediary molecule; DNA codes for RNA, which, in turn, codes for protein. More recently, scientists found that of the three billion base pairs in the human genome, only two per cent encode proteins. Read more. . .


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