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Pant Pushes for De-Escalated Options, Targeted Therapy in Pancreatic Cancer

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Chemotherapy has been a mainstay in advanced pancreatic cancer, but it can be challenging for patients to tolerate, according to Shubham Pant, MD, who added that de-escalated maintenance approaches could be one way to help patients preserve their quantity and quality of life.

For example, data from the phase II PRODIGE 35-PANOPTIMOX trial showed comparable overall survival (OS) among previously untreated patients with advanced disease who received 6 months of FOLFIRINOX versus 4 months of FOLFIRINOX followed by 5-fluorouracil/leucovorin (LV5FU2).  Read more . . . 

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