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Adaptive EGF expression sensitizes Pancreatic Cancer Cells to Ionizing Radiation Through Activation of the Cyclin D1/P53/PARP Pathway

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The present study demonstrated that adaptive expression of epidermal growth factor (EGF) following exposure to ionizing radiation (IR) may induce radiosensitization of pancreatic cancer (PC) cells through induction of the cyclin D1/P53/poly(ADP‑ribose) polymerase pathway.

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