COMPASS: Genomic Profiling Could Guide Treatment in Advanced Pancreatic Cancer

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As part of our coverage of the 2018 Gastrointestinal Cancers Symposium, held January 18–20 in San Francisco, we are speaking with Kyaw L. Aung, MBBS, PhD, a clinical fellow at the Princess Margaret Cancer Centre in Toronto.

Dr. Aung presented updated data from the COMPASS trial which used whole-genome sequencing and RNA sequencing to analyze the tumors of patients with advanced pancreatic ductal adenocarcinoma to identify possible first-line treatments.

Cancer Network: First, can you tell us about the design of the COMPASS study? What is unique about the study, either as a pancreatic cancer study or as a cancer trial in general?

Dr. Aung: The COMPASS study was designed to acquire a fresh tumor biopsy from patients with advanced pancreatic cancer, and both locally advanced and metastatic patients were included in this trial. Read more . . .


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