In terms of prevalence, NETs represent the second commonest gastrointestinal malignancy after colorectal cancer.
In fact, the graph of the SEER database from 2004 indicated that the rate of incidence increase was faster than any other cancer on the planet, this particular rise in incidence was mainly attributed to lung, small intestine, and rectal NETs (but see latest SEER database output on you read on). However, since the World Health Organisation’s revised classification of Neuroendocrine Neoplasms in 2010, there would be a significant increase if this data exercise was run again. This is due to the abandonment of the division between benign and malignant NETs following the 2010 declaration that all NETs now have malignant potential and are graded accordingly. The 2004 SEER data compiled did not take into account benign NETs. Read more . . .