Novel gene-hunting method implicates new culprit in pancreatic cancer
Using an innovative approach to identify a cancer’s genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.
The team, led by scientists at The University of Texas MD Anderson Cancer Center, found the gene WDR5 protects pancreatic tumors from DNA damage, working with the previously known cancer-promoting gene called Myc to help tumors thrive.