Blog

27 Articles

Kim Reiss Binder
Research
November 1, 2018 • 5 Min

PARP Inhibitors for Pancreatic Cancer Maintenance Treatment

Dr. Kim Reiss Binder is leading a clinical trial of maintenance treatment with the PARP inhibitor rucaparib, for patients who carry the BRCA mutation.

Doron Broman, center left, surrounded by others includ Dr. Kimmie Ng on the far right.
Survivor Stories
October 23, 2018 • 3 Min

Molecular Sequencing Leads to Customized Treatment

When Florida resident Doron Broman was diagnosed with stage IV pancreatic cancer, his decision to get treated in Boston gave him access a PARP inhibitor for maintenance.

Dr. Aimee Lucas
Research
October 19, 2018 • 4 Min

Which Is the Best Screening Method for Pancreatic Cancer?

Dr. Aimee Lucas outlines the pros and cons of various screening methods that can be used for pancreatic cancer, and who should be using them.

Dr. Paul Silverstein, pancreatic cancer patients
Survivor Stories
June 13, 2018 • 7 Min

Aiming to be More than a Statistic

Dr. Paul Silverstein knew that he needed genomic testing, immunotherapy, and a clinical trial in his battle with pancreatic cancer.

Illustration of a protein that includes the BRCA2 mutation. The illustration includes spirals in brown, strands in purple, blue directional arrows, and green, yellow, red, and blue circles.
Research
June 27, 2017 • 2 Min

A Maintenance Trial for Patients with BRCA or PALB2 Mutations

A clinical trial examines whether the PARP inhibitor rucaparib can work as a maintenance drug for pancreatic cancer patients with BRCA or PALB2 mutations.

A paper model of DNA to illustrate genetic testing
Research
May 9, 2017 • 2 Min

Treating BRCA-Negative Pancreatic Cancer Patients with a Family Cancer History Similar to BRCA Carriers

A clinical trial looks at the effectiveness of a PARP inhibitor in BRCA-negative pancreatic cancer patients with a family history BRCA-type cancers.

Pancreatic cancer survivor Steve Merlin
Survivor Stories
May 4, 2017 • 5 Min

A Clinical Trial Matches My Genetics

Steven Merlin learned that he carried the BRCA2 mutation after he developed pancreatic cancer. He researched and found a clinical trial for BRCA carriers.

Pancreas cross section embedded in paraffin wax, stained blue and purple, 100x magnification.
Research
January 16, 2017 • 2 Min

Comparing a Standard Chemotherapy With and Without a PARP Inhibitor

A clinical trial compares standard chemotherapy with and without the addition of a PARP inihibitor, for patients whose pancreatic cancer is spreading again.

Illustration of the twisting spirals of two DNA double helices in royal blue and purple on a turquoise colored background
Research
October 18, 2016 • 2 Min

A New Drug Combination to Control Advanced Pancreatic Cancer

A clinical trial for pancreatic cancer patients with the BRCA mutation tests the effectiveness of standard treatment plus a PARP inhibitor.

Microscope image of four pancreatic cells with pinkish edges and green centers, against a dark background
Research
October 10, 2016 • 2 Min

A Novel Combination to Slow Pancreas Tumors that Cannot Be Surgically Removed

Can a combination of standard drugs, a PARP inhibitor, and intensity modulated radiation therapy to slow pancreatic tumor growth?

Microscopy image of a tumor section (obtained from a mouse tumor model) shows the blue-stained nanoparticles selectively accumulating in the peripheral tumor area and then penetrating into tumor cells
Research
August 18, 2016 • 2 Min

Exploring the Effectiveness of an Experimental Class of Drug

Does adding a PARP inhibitor drug to standard treatment help control the spread of advanced pancreatic cancer in patients with the BRCA mutation?

test tubes with red and yellow liquids
Research
July 26, 2016 • 2 Min

Maintenance Chemotherapy Trial for Pancreatic Cancer Patients with the BRCA Mutation

A clinical trial for patients with BRCA mutations uses a PARP inhibitor as part of the maintenance chemotherapy experimental treatment.

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