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121 Articles
Finding a Safe Dose of a New Drug for Some Types of Solid Tumors
LMB-100 is a lab-created protein that targets mesothelin. It is being tested against pancreatic cancer and other solid tumors in a clinical trial.
Personalized Immunotherapy Vaccine for Pancreatic Cancer
Researchers are creating a personalized vaccine to stimulate a pancreatic cancer patient’s immune system after surgery and chemotherapy.
New Research Sheds Light on Hot and Cold Tumors
Dr. Ben Z. Stanger and his team are finding links between the number of T cells a tumor has and the effectiveness of immunotherapy.
I Have So Much to Live For
Mary Gillam knew that she had to fight after her pancreatic cancer diagnosis. She traveled to where she would get the best treatment and a clinical trial.
Before And After: My Pancreatic Cancer
Randall Swan did his homework on the best treatments and clinical trial options in order to do battle with pancreatic cancer.
Targeting Tumor Proteins Specific to Pancreatic Cancer Cells
A clinical trial tests the safety and effectiveness of tumor-associated antigen-specific cytotoxic T lymphocytes, which target specific tumor proteins.
Aiming to be More than a Statistic
Dr. Paul Silverstein knew that he needed genomic testing, immunotherapy, and a clinical trial in his battle with pancreatic cancer.
Testing the Effectiveness of Immunotherapy Added to a New Drug Combination
Researchers are testing a drug combination that adds immunotherapy to standard drugs used to treat pancreatic cancer and an antimalarial drug.
Testing Immunotherapy for Safety Before and After Pancreatic Cancer Removal
Researchers are testing a new monoclonal antibody to see if it helps patients with pancreatic tumors that can be surgically removed.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Immunotherapy for Pancreatic Neuroendocrine Tumors
A clinical trial combines the immunotherapy drug pembrolizumab with lanreotide, a drug typically used to treat pancreatic neuroendocrine tumors.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Neoantigens Provide New Hope for Pancreatic Cancer Treatments
Vinod Balachandran’s team identified increased T cells in the tumors of long-term pancreatic cancer survivors, with a role for neoantigens in immunotherapy.
Noninvasive Surgery and a New Drug to Stop Pancreatic Tumors
A clinical trial combines irreversible electroporation (IRE) and immunotherapy to see if the duo is effective against locally advanced pancreatic cancer.
The ABCs of Genetic Testing
There are a number of different genetic mutations that can cause familial pancreatic cancer. This article explains some of the most common ones.