Genetic Mutations
146 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
Reeducating Myself About Pancreatic Cancer
Martin Hynes knew all about pancreatic cancer–as a research director he worked on the development of Gemzar. He was able to have a Whipple and is doing well.
RNA Precision Trial for Pancreatic Cancer Opens At Columbia
Dr. Andrea Califano leads a precision oncology clinical trial of the OncoTreat platform, which looks at proteins to determine treatment.
The Pancreatic Standard of Care is No Longer So Standard
Do you want to understand more about how your doctor chooses your treatments? Learn about the standard of care for pancreatic cancer.
Comprehensive Molecular Test Helps Classify Pancreatic Cysts
Dr. Aatur Singhi and colleagues are developing a test to help determine whether pancreatic cysts are likely to turn cancerous.
Finding More Clues about Circulating Tumor DNA
Researcher Dr. Gehan Botrus looks at circulating tumor DNA for genetic information on a patient’s pancreatic cancer to personalize treatment.
Testing Vitamin C as a Cancer Killer
Lewis Cantley’s team is starting clinical trials of vitamin C to gain more information about its role in stopping cancer.
Can a Pancreatic Cancer Screening Test Become a Reality?
Dr. Felice Schnoll-Sussman discusses screening options for pancreatic cancer and criteria for people who might want to get screened.
Targeting the Undruggable KRAS Protein
Dr. Shubham Pant is focusing his research on effective treatments for the KRAS mutation, found in 90% of pancreatic cancers.
Too Busy Living Large!
Jane Eshbaugh regularly participated in Roswell Park Cancer Center’s annual fundraising bike ride, not knowing that one day she would be a patient.
BRCA Mutation Determines My Pancreatic Cancer Treatment
Chris Treubert started with one type of chemotherapy but when the results of genetic testing showed a BRCA mutation he changed treatment.
Drafting Your Health Care Team
If you have pancreatic cancer, a treatment team of experts from across the medical profession will make sure you get the best care.
Study Reveals Molecular Differences in Young-Onset Pancreatic Cancer
There has been a notable increase in cases of young onset pancreatic cancer. Dr. Jashodeep Datta and team are exploring why this is happening.
Newly Discovered Protein Complex in RAS Pathway May Provide a Treatment Target
Dr. Andrew Aguirre and other researchers from Dana-Farber and the Broad Institute are looking at the RAS pathway for a new target.
Each Person Is a Statistic of One
When Miggie Olsson was diagnosed with stage IV pancreatic cancer she opted for a science-based unusual treatment plan to have a chance at survival.
Pancreatic Cancer and Family History
Dr. Diane Simeone is developing a tablet-based family history survey to identify patients with a genetic-based risk for developing pancreatic cancer.