Genetic Mutations
146 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
BRCA Mutations and Pancreatic Cancer
Let’s Win, the National Alliance for Hispanic Health, and the Basser Center for BRCA teamed up to present a webinar on BRCA mutations and pancreatic cancer.
An Expanded Access Trial for Cancer Patients with Specific Mutations
An investigational drug is being used in an expanded access trial for advanced pancreatic and other cancer patients with specific genetic changes.
Genetic Testing and Molecular Profiling Can Guide Treatment
Watch our webinar on Genetic Testing and Molecular Profiling to learn from experts and patients why this is so important.
Studying One Family’s Mutations May Change Pancreatic Cancer Treatment and Prevention
Dr. Sahar Nissim is studying the genetic mutations in one family predisposed to pancreatic cancer, to find new ways to combat the disease.
New Study to Get More Minorities Involved in Genetic Testing
Dr. Nicolette Rodriguez leads the REGENERATE study to find the best ways to get more Black and Latinx Americans genetic testing for cancer.
Representing Genetic and Clinical Diversity in Pancreatic Cancer
Dr. Kentaro Sudo explores the possible causes for different responses to drugs among ethnic groups, pointing to the need for clinical diversity in trials.
Testing a PARP Inhibitor for Metastatic Pancreatic Cancer Patients with DNA Repair Mutations
Researchers are testing a PARP inhibitor that is effective for cancers in pancreatic cancer patients with DNA repair mutations.
Focusing on a Drug that Treats Specific Tumor Mutations
A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.
CRISPR: A New Tool to Help Understand Cancer-Linked Mutations
Lukas Dow, Ph.D., is using CRISPR technology to find better ways to fight cancer by editing the genome.
Testing a Signal-Inhibiting Drug on Tumors with Specific Mutations
A new drug for certain tumor mutations is being tested in a type of clinical trial called a basket trial, which matches tumor genetics and drugs.
GENERATE Trial Expands Eligibility
Dr. Sapna Syngal explains the expanded eligibility standards for the GENERATE Study for genetic testing of pancreatic cancer patients and relatives.
Peace of Mind Through Genetic Testing of Pancreatic Cyst Fluid
A patient with pancreatic cysts took a test that looks at genetic markers in the cyst fluid, to determine her risk of developing cancer.
Tumor RNA Testing Leads to Treatment with a New Drug
When treatment stopped working for Adam Deal, genetic testing of his tumor RNA found a mutation that made him eligible to try a new drug.
Family History
Does it Run in My Family? The connection between your family’s medical history and pancreatic cancer As you may already know, cancer can run in families. In fact, people carrying certain genetic mutations have an increased risk of getting cancers including breast, colon, prostate, ovarian, and pancreatic cancer. All told, researchers estimate that known genetic […]
New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors
A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.