Genetic Mutations

390 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Research
October 17, 2019 • 3 Min

Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer

Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.

Survivor Stories
June 1, 2023 • 4 Min

No One Fights Alone

Because of her grandfather, Rhonda Havig knew she had a family history of pancreatic cancer. But her own diagnosis was still a surprise.

Research
May 23, 2024 • 4 Min

Study Reveals Molecular Differences in Young-Onset Pancreatic Cancer

There has been a notable increase in cases of young onset pancreatic cancer. Dr. Jashodeep Datta and team are exploring why this is happening.

Research
April 3, 2020 • 5 Min

Tumor Biology Matters

Dr. Lynn Matrisian of PanCAN, explains that molecular profiling of a pancreatic cancer patient’s tumor can show which treatment will work best.

Survivor Stories
August 15, 2016 • 5 Min

The Impact of BRCA Is Broader Than Breast and Ovarian Cancer

Rona Greenberg discusses the impact of BRCA2 on her family, and her search for the best clinical trial for her needs after her pancreatic cancer diagnosis.

Survivor Stories
April 2, 2018 • 4 Min

Genomic Testing of Pancreatic Tumor Leads to an Important Discovery

Connie Waxman learned the value of palliative care after chemotherapy, radiation, and a pancreatectomy for pancreatic cancer; then she had genomic testing.

Survivor Stories
March 8, 2019 • 5 Min

Facing Pancreatic Cancer and Making the Most of Borrowed Time

With a young family, Justin Baker is hoping for more time because he has a genetic mutation that favors certain treatments.

Survivor Stories
June 6, 2019 • 5 Min

Younger Brother’s Pancreatic Cancer Leads to Regular Screening for his Oldest Brother

When Scott Nelson was diagnosed with pancreatic cancer, oldest brother Steve began regular screening, which lead to his early diagnosis.

Survivor Stories
October 9, 2023 • 4 Min

Changing Course Midstream

Barbara Green wasn’t happy with her doctors, so she took the advice of her support group, was an advocate for herself, and changed doctors.

Survivor Stories
March 15, 2024 • 4 Min

Sometimes Things Get Worse Before They Get Better

Matthew Rosenblum thought his time was limited after a pancreatic cancer diagnosis at age 32, but he’s a BRCA2 carrier, which opened treatment options.

Research
January 2, 2024 • 5 Min

Progress and Promise—Research in 2023

What advances were made in 2023 for pancreatic cancer treatments? Where is research headed in the coming year?

Page
August 2, 2022 • 3 Min

Pancreatic Cancer Basics

Learn the Basics Getting diagnosed with pancreatic cancer is overwhelming. Besides not feeling well, you are thrown into a world with treatments, procedures, and words you don’t know, while facing major decisions and a very serious disease. Here you can find comprehensive explanations, including different treatments and questions to ask. To learn more about first […]

Research
April 29, 2020 • 5 Min

High-Dose Vitamin C Targeting KRAS and BRAF in Pancreatic Cancer

Learn how Dr. Manish Shah is leading clinical trials using high-dose Vitamin C to target KRAS and BRAF mutations in pancreatic cancer.

Survivor Stories
December 21, 2017 • 5 Min

Using the Energy Around Me to Help Me Heal

Judith Glaser’s genetic mutation influenced her chemotherapy and radiation treatments, supported by the healing energy of friends.

Survivor Stories
January 3, 2025 • 2 Min

Early Diagnosis Is Important

Jami Curry knew her family history included breast and pancreatic cancer, so she was alert to any health changes.