Genetic Mutations
390 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
Targeting the Undruggable KRAS Protein
Dr. Shubham Pant is focusing his research on effective treatments for the KRAS mutation, found in 90% of pancreatic cancers.
Highlights from the 2025 AACR Annual Meeting
Drugs to target KRAS, better imaging for earlier detection, and cachexia prediction are among the research highlights from AACR 2025.
Extensive Family History and Genetic Testing Leads to Early Detection
Sidney Levinson and his doctor were aware of his BRCA1/2 mutations so when an MRI was recommended for screening, Sidney did it.
ASCO Annual Conference: Highlights in Pancreatic Cancer Research
Dr. Allyson Ocean reviews some of the latest pancreatic cancer research results, including new treatments for some patients.
Pancreatic Cancer Caught Early Because of My Vigilance
Beverly Leighton joined a screening study and underwent genetic testing because of her family history of pancreatic cancer.
Comprehensive Molecular Test Helps Classify Pancreatic Cysts
Dr. Aatur Singhi and colleagues are developing a test to help determine whether pancreatic cysts are likely to turn cancerous.
Questions to Ask Before You Begin Chemotherapy
Do you want to better understand your pancreatic cancer treatment? Dr. Andrew Hendifar outlines important questions to ask before starting chemotherapy.
An Expanded Access Trial for Cancer Patients with Specific Mutations
An investigational drug is being used in an expanded access trial for advanced pancreatic and other cancer patients with specific genetic changes.
Personalized Treatment Plans in the Fight Against PC
David Dessert explains that his aunt’s genetic testing for BRCA2 mutation directed his own treatment for pancreatic cancer.
A Second Opinion Makes the Difference
Irma Infante refused to give up after a stage IV pancreatic cancer diagnosis. She went for a second opinion and better treatment options.
Pancreatic Cancer Research Builds Upon Strengths
The September 2023 AACR Special Conference on Pancreatic Cancer focused on the latest research in KRAS, chemotherapy, and cachexia, among other topics.
Newly Diagnosed
What to Do If You Have Recently Been Diagnosed with Pancreatic Cancer You or someone you love has been diagnosed with pancreatic cancer. Now what? First, know that you are not alone in this overwhelming moment. No one should have to face pancreatic cancer without trusted resources and hope. Let’s Win is a go-to guide […]
A New Triple Combination for Tumors with BRCA1/2 or PALB2 Mutations
A clinical trial is comparing a two-drug combination with a three-drug combination to see which works better for genetic mutations.
Three Ways to Be your Own Best Health Advocate
Leslie Michelson recommends putting together a health care team of friends, advocates and physicians for the best possible care after a cancer diagnosis.
Looking Back at the Year in Research: 2019
Research highlights of 2019 include: approval of a PARP inhibitor, artificial intelligence to diagnose pancreatic cysts, and updated radiation guidelines.