Genetic Mutations
359 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
Comprehensive Molecular Test Helps Classify Pancreatic Cysts
Dr. Aatur Singhi and colleagues are developing a test to help determine whether pancreatic cysts are likely to turn cancerous.
Questions to Ask Before You Begin Chemotherapy
Do you want to better understand your pancreatic cancer treatment? Dr. Andrew Hendifar outlines important questions to ask before starting chemotherapy.
Personalized Treatment Plans in the Fight Against PC
David Dessert explains that his aunt’s genetic testing for BRCA2 mutation directed his own treatment for pancreatic cancer.
A Second Opinion Makes the Difference
Irma Infante refused to give up after a stage IV pancreatic cancer diagnosis. She went for a second opinion and better treatment options.
An Expanded Access Trial for Cancer Patients with Specific Mutations
An investigational drug is being used in an expanded access trial for advanced pancreatic and other cancer patients with specific genetic changes.
Pancreatic Cancer Research Builds Upon Strengths
The September 2023 AACR Special Conference on Pancreatic Cancer focused on the latest research in KRAS, chemotherapy, and cachexia, among other topics.
Newly Diagnosed
What to Do If You Are Newly Diagnosed with Pancreatic Cancer You or someone you love has been diagnosed with pancreatic cancer. Now what? First, take a breath and know that you are not alone in this overwhelming moment. Let’s Win has the most up-to-date information, research, and resources to help you make informed decisions […]
A New Triple Combination for Tumors with BRCA1/2 or PALB2 Mutations
A clinical trial is comparing a two-drug combination with a three-drug combination to see which works better for genetic mutations.
Three Ways to Be your Own Best Health Advocate
Leslie Michelson recommends putting together a health care team of friends, advocates and physicians for the best possible care after a cancer diagnosis.
Looking Back at the Year in Research: 2019
Research highlights of 2019 include: approval of a PARP inhibitor, artificial intelligence to diagnose pancreatic cysts, and updated radiation guidelines.
Finding More Clues about Circulating Tumor DNA
Researcher Dr. Gehan Botrus looks at circulating tumor DNA for genetic information on a patient’s pancreatic cancer to personalize treatment.
Don’t Let Doctors Tell You Nothing’s Wrong
After a long road to diagnosis Brandon Stone learned he has a BRCA2 genetic mutation that impacts his treatment.
Targeted Therapy for Cancers Carrying the PALB2 Mutation
Researchers are testing a type of targeted therapy called a PARP inhibitor for cancers carrying the PALB2 mutation.
Listen to Your Body
When Roxanne Waling discovered she had pancreatic cancer she underwent genetic testing. She found she was a BRCA2 carrier, which influenced her post-treatment decisions about her health.
ASCO GI Symposium Features a Broad Range of Pancreatic Cancer Research
Researchers at ASCO GI 2024 reported on research in health disparities, KRAS and other genetic mutations, and novel treatments.