Genetic Mutations
391 articles
Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.
Chemotherapy Plus Stem Cell Infusion and Vitamins for BRCA Mutated Pancreatic Cancer
A clinical trial for pancreatic cancer patients with a BRCA mutation uses a combination of chemotherapy, vitamins, and stem cells.
Genetic Testing Changed My Chemo Protocol
Greg Jacobson’s family has an extensive history of cancer. After a pancreatic cancer diagnosis, genetic testing found the mutation for Lynch syndrome.
ASCO 2023: Pancreatic Cancer Research Update
The pancreatic cancer research reports from ASCO 2023 focused on different chemotherapy combinations, including immunotherapy.
Molecular Profiling: Getting to Know Your Tumor
Dr. Johanna Bendell explains the value of molecular profiling, which can indicate the best type of chemotherapy for your tumor.
Representing Genetic and Clinical Diversity in Pancreatic Cancer
Dr. Kentaro Sudo explores the possible causes for different responses to drugs among ethnic groups, pointing to the need for clinical diversity in trials.
Understanding a Family’s Risk for Pancreatic Cancer
A tumor registry studies the genetics of pancreatic cancer to determine risk factors for families.
Taking Nothing For Granted
After Whipple surgery and chemoradiation, Susan Zbacnik had molecular profiling, genetic testing, and joined an Immunotherapy clinical trial.
Meet the Researcher: Nicolette Juliana Rodriguez, M.D., M.P.H.
Learn more about the research interests of Nicolette Rodriguez, M.D., M.P.H., one of the young investigators Let’s Win sponsored at AACR.
Pancreatic Cancer and Family History
Dr. Diane Simeone is developing a tablet-based family history survey to identify patients with a genetic-based risk for developing pancreatic cancer.
New Biopsy Shows Promise For Pancreatic Cancer Patients
Trovagene is developing a liquid biopsy for pancreatic cancer patients, to allow doctors to test for cancer and track treatment response.
Tailoring My Treatment to My Tumor Genetics
After diagnosis with pancreatic cancer, Sharon Simone had her tumor analyzed. The report on her tumor genetics determined her treatment.
A Genetic Mutation Aids My Treatment
Malcolm Robertson carries the BRCA2 mutation, so when he was diagnosed with pancreatic cancer, platinum-based chemo was part of his treatment.
Genetic Testing Leads Me to a PARP Inhibitor Trial
Harvey Parker had genetic testing as part of his initial pancreatic cancer treatment. The BRCA2 mutation led him to a PARP inhibitor clinical trial.
BRCA Mutation Determines My Pancreatic Cancer Treatment
Chris Treubert started with one type of chemotherapy but when the results of genetic testing showed a BRCA mutation he changed treatment.
Newly Discovered Protein Complex in RAS Pathway May Provide a Treatment Target
Dr. Andrew Aguirre and other researchers from Dana-Farber and the Broad Institute are looking at the RAS pathway for a new target.