Genetic Mutations and Family History
704 articles
Using Tumor Tissue Samples to Break Down Assumptions About Pancreatic Cancer
Dr. Christine Iacobuzio-Donahue uses tumor tissue samples to study how pancreatic cancer tumors develop, so she can find ways to stop the disease.
Treating BRCA-Negative Pancreatic Cancer Patients with a Family Cancer History Similar to BRCA Carriers
A clinical trial looks at the effectiveness of a PARP inhibitor in BRCA-negative pancreatic cancer patients with a family history BRCA-type cancers.
BRCA Mutations and Pancreatic Cancer
Let’s Win, the National Alliance for Hispanic Health, and the Basser Center for BRCA teamed up to present a webinar on BRCA mutations and pancreatic cancer.
Understanding Who Is at High Risk for Pancreatic Cancer
Who is high-risk for pancreatic cancer? Oncologist Dr. Matthew Yurgelun explains high-risk populations and what steps to take if you meet the criteria.
Pancreatic Cancer Caught Early Because of My Vigilance
Beverly Leighton joined a screening study and underwent genetic testing because of her family history of pancreatic cancer.
Leaning into the Fight: My Battle with Pancreatic Cancer
Despite an extensive family history of pancreatic cancer, Deanna Burney’s doctors did not keep a close eye on her pancreatic cyst.
My Journey with Pancreatic Cancer
Dr. Robert Wagar lost both parents to pancreatic cancer. When his wife found an article about a surveillance study he had an MRI, which found a lesion.
Genetic Testing Changed My Chemo Protocol
Greg Jacobson’s family has an extensive history of cancer. After a pancreatic cancer diagnosis, genetic testing found the mutation for Lynch syndrome.
RASolute 302 Trial for KRAS and Other RAS Mutations Recruiting at Multiple Sites
Dr. Hani Babiker is optimistic about the new drug to treat patients with KRAS mutations, now in a phase III trial.
Cherishing the Simple Things
Elizabeth O’Connor has a PALB2 genetic mutation so her stage IV pancreatic cancer has responded to immunotherapy.
What Caused My Pancreatic Cancer?
Despite no known genetic link, Steven Robinson is the fourth member of his family on his mother’s side to get pancreatic cancer.
A Potential Role for PARP Inhibitors in Pancreatic Cancer
Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.
Understanding a Family’s Risk for Pancreatic Cancer
A tumor registry studies the genetics of pancreatic cancer to determine risk factors for families.
Most Cancer Mutations Are Random DNA Mistakes
In a large study, Dr. Bert Vogelstein of Johns Hopkins found that a majority of cancers, including pancreatic cancer, are caused by random mutations of DNA.
Genetic Testing Leads Me to a PARP Inhibitor Trial
Harvey Parker had genetic testing as part of his initial pancreatic cancer treatment. The BRCA2 mutation led him to a PARP inhibitor clinical trial.