Genetic Mutations and Family History

73 articles

Research
March 21, 2022 • 5 Min

New Study to Get More Minorities Involved in Genetic Testing

Dr. Nicolette Rodriguez leads the REGENERATE study to find the best ways to get more Black and Latinx Americans genetic testing for cancer.

Research
June 26, 2018 • 2 Min

Early Detection Trial for People at Higher Risk of Pancreatic Cancer

Relatives of pancreatic cancer patients or people who carry certain mutations can participate in an early detection clinical trial.

Research
May 15, 2024 • 2 Min

A New Triple Combination for Tumors with BRCA1/2 or PALB2 Mutations

A clinical trial is comparing a two-drug combination with a three-drug combination to see which works better for genetic mutations.

Research
July 8, 2025 • 6 Min

Treating Cancer By Mutation, Not by Tumor Location

Dr. Conan Kinsey outlines the latest basket trials, which focus on tumor mutation, not the location of the cancer.

Research
July 27, 2017 • 4 Min

Most Cancer Mutations Are Random DNA Mistakes

In a large study, Dr. Bert Vogelstein of Johns Hopkins found that a majority of cancers, including pancreatic cancer, are caused by random mutations of DNA.

Research
July 14, 2017 • 5 Min

An Immunotherapy Game Changer

Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.

Research
November 8, 2016 • 4 Min

BRCA’s Role in Pancreatic Cancer Investigated

The relationship between BRCA and pancreatic cancer, and how that affects treatment, is the focus of clinical trials looking at PARP inhibitors.

Research
January 29, 2024 • 6 Min

ASCO GI Symposium Features a Broad Range of Pancreatic Cancer Research

Researchers at ASCO GI 2024 reported on research in health disparities, KRAS and other genetic mutations, and novel treatments.

Screening and Early Detection
October 21, 2016 • 5 Min

Can a Pancreatic Cancer Screening Test Become a Reality?

Dr. Felice Schnoll-Sussman discusses screening options for pancreatic cancer and criteria for people who might want to get screened.

Research
November 6, 2020 • 2 Min

An Expanded Access Trial for Cancer Patients with Specific Mutations

An investigational drug is being used in an expanded access trial for advanced pancreatic and other cancer patients with specific genetic changes.

Research
December 3, 2020 • 7 Min

Artificial Intelligence and Early Detection of Pancreatic Cancer

How can AI be used in the early detection of pancreatic cancer? Dr. Michael Rosenthal reviews the current state of the field.

Research
May 12, 2020 • 7 Min

Earlier Detection of Pancreatic Cancer: A Marathon, Not A Sprint

Dino Verrelli of Project Purple joins with Dr. Diane Simeone on the PRECEDE Consortium to develop earlier detection and new pancreatic cancer treatments.

Research
August 22, 2023 • 5 Min

New AI Tool Brings Hope in Quest for Earlier Detection

Can AI help catch pancreatic cancer at an earlier stage? Dr. Michael Rosenthal and others are working on an AI tool to do just that.

Research
February 1, 2022 • 7 Min

Liquid Biopsies: What You Should Know

Three different liquid biopsy blood tests are under development or now available for pancreatic and other cancers.

Research
October 22, 2019 • 2 Min

Searching for Potential Pancreatic Cancer Blood Biomarkers

Researchers are using blood samples to follow people considered at risk for developing pancreatic cancer in a trial looking for early detection biomarkers.