Clinical Trials

Clinical trials should be every patient's starting point when it comes to pancreatic cancer. Find out about trials that are available today, and the cutting-edge research available to patients.

149 Articles

DNA helix made of metal, plastic and stained glass
Research
January 10, 2020 • 2 Min

Drug Combination to Combat Pancreatic and other Gastrointestinal Cancers

Researchers are testing a drug combination of TAS-102, an approved drug for colorectal cancer, and nanoliposomal irinotecan, on gastrointestinal cancers.

Test tubes with blue and yellow liquids in them
Research
December 13, 2019 • 3 Min

Testing Treatment Combinations to Make Surgery More Effective

Can losartan (a high blood pressure drug) and immunotherapy combined with standard chemotherapy and radiation be an effective combination against pancreatic cancer?

photomicrograph of red blood cells
Research
September 26, 2019 • 2 Min

Comparing Treatment Delivery Methods for Locally Advanced Pancreatic Cancer

A clinical trial compares intravenous chemotherapy delivery with intra-arterial chemotherapy to see which is more effective for pancreatic cancer.

Killer T cells
Research
September 10, 2019 • 4 Min

CAR T Cell Trial Targets Mesothelin

In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.

Blue green and pink abstract lines and dots on a black background
Research
August 30, 2019 • 2 Min

Adding A Noninvasive Surgical Technique to Standard Treatment for Locally Advanced Pancreatic Cancer

A clinical trial compares standard treatment plus irreversible electroporation to standard treatment alone for locally advanced pancreatic cancer.

microscope image of the structure of blood vessel endothelium with the proteins that hold the shapes in red
Research
June 14, 2019 • 2 Min

Testing a New Drug to Attack Pancreatic Tumor Blood Vessels

A clinical trial is testing a new drug combination that damages the tumor blood vessels and allows chemotherapy drugs to enter the tumor.

Precancerous pancreatic cells in mice
Research
May 20, 2019 • 2 Min

A New Drug to Target Cancer Cell Enzymes

Researchers are testing a drug that targets the enzymes that help generate energy for cell division, to disrupt pancreatic cancer cell multiplication.

multicolor abstract computer created image of series of squares that look like a DNA helix
Research
February 7, 2019 • 2 Min

Testing a Different Approach to Pancreatic Cancer Treatment

A drug that is epigenetic therapy, which alters how DNA behaves, is being tested in a clinical trial for pancreatic cancer.

black disc in motion against a yellow background
Research
December 12, 2018 • 2 Min

Electric Fields to Enhance Pancreatic Cancer Chemotherapy

A clinical trial uses electric fields to help slow the growth of tumor cells, In a clinical trial for pancreatic cancer patients.

Grayscale image of round lab containers with dark agar medium arranged in rows.
Research
October 16, 2018 • 2 Min

Finding a Safe Dose of a New Drug for Some Types of Solid Tumors

LMB-100 is a lab-created protein that targets mesothelin. It is being tested against pancreatic cancer and other solid tumors in a clinical trial.

laboratory glassware
Research
September 12, 2018 • 3 Min

Tough Tortoise of a Drug Beating Metastatic Pancreatic Cancer

Rexahn Pharmaceuticals is testing RX-3117, a slow-releasing drug similar to gemcitabine, in a clinical trial for metastatic pancreatic cancer patients.

White net mask in close up
Research
August 29, 2018 • 2 Min

Radiotherapy Implant plus Standard Chemotherapy

The OncoSil radiotherapy implant device is being tested on pancreatic cancer in a clinical trial that combines it with standard chemotherapy.

looking down on top of culture test tubes with red tops, against a light blue background
Research
August 3, 2018 • 2 Min

Targeting Tumor Proteins Specific to Pancreatic Cancer Cells

A clinical trial tests the safety and effectiveness of tumor-associated antigen-specific cytotoxic T lymphocytes, which target specific tumor proteins.

Dr. Alok Khorana
Research
July 31, 2018 • 4 Min

A Combination of Neoadjuvant Chemotherapy and Radiation Shows Promise

Dr. Alok Khorana discusses the results of clinical trials of neoadjuvant chemotherapy and radiation to make surgery more effective.

orange colored clear vitamin D pills in a circle against an orange background
Research
July 23, 2018 • 2 Min

A New Combination Chemotherapy Before Surgery

A new clinical trial adds vitamin D to standard of care chemotherapy before surgery, to make pancreatic cancer tumors more removable.