Clinical Trials

104 Articles

clear test tubes with black caps and wavy lines on them sit upright in a solid metal rack, with red, white, and blue light shined on them
Research
October 9, 2017 • 1 Min

Investigating a Drug Used for Other Cancers

In a clinical trial, researchers are adding the drug decitabine to gemcitabine, for patients with advanced cancer that is not responding to treatment.

Abstract image of roundish shapes packed together, in shades of yellow to black colorsv
Research
September 26, 2017 • 2 Min

Chemotherapy, Immunotherapy, and Radiation for Locally Advanced Pancreatic Cancer

A clinical trial combines chemotherapy, immunotherapy, including a pancreas vaccine, and SBRT to stop locally advanced pancreatic cancer.

Microscope slide of the pancreas, with the some structures in purple and some in pink
Research
August 30, 2017 • 2 Min

More Effective Focused Radiation Therapy and Chemotherapy for Locally Advanced Pancreatic Cancer

A clinical trial tests whether adding Zometa makes chemotherapy and stereotactic body radiation therapy (SBRT) more effective against pancreatic cancer.

Photo of pill capsules with blue and beige ones in focus in the front, and out of focus pills in brown, pink and brown, and blue and beige in the background
Research
August 17, 2017 • 2 Min

Presurgical Treatment for Pancreatic Cancer That Is Removable

A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.

Magnified slide of human pancreas cells, stained in aqua color with a dark outline around some of the rounded cells
Research
July 24, 2017 • 2 Min

Trying a New Type of Treatment to Stop Advanced Pancreatic Cancer

Researchers test the chemotherapy combination of AM0010 and FOLFOX as a second-line therapy for people with metastatic pancreatic cancer.

Glass flasks with wider bottoms and narrower tops sit on a table; the left flask is partway filled with dark green clear liquid, the right flask contains a lighter bright green clear liquid
Research
July 11, 2017 • 2 Min

Testing the Safety of a New Chemotherapy and Radiation Combination

A clinical trial tests the effectiveness of adding PEGPH20 to standard chemotherapy and radiation in patients with locally advanced pancreatic cancer.

abstract image of stem cells with a large area of red, interspersed with blue, and bright green areas at the bottom of the image
Research
June 15, 2017 • 2 Min

Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer

A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.

Microscope image of pancreatic cells in purple and teal on a dark background
Research
April 18, 2017 • 2 Min

Testing a Signal-Inhibiting Drug on Tumors with Specific Mutations

A new drug for certain tumor mutations is being tested in a type of clinical trial called a basket trial, which matches tumor genetics and drugs.

Black and white photo of clear plastic disks stacked randomly
Research
April 5, 2017 • 2 Min

Comparing Chemotherapy and Radiation Regimens to Prevent Recurrence of Pancreatic Cancer

A clinical trial compares standard chemotherapy with gemcitabine to the combination of chemotherapy with capecitabine and radiation.

Microscope image of mouse pancreas duct cancer with different parts of the cells stained blue or red, against a dark background
Research
February 22, 2017 • 2 Min

Using a Virus to Infect and Destroy Pancreatic Cancer Cells

A clinical trial tests the combination of standard chemotherapy plus a common cold virus that has been modified to kill cancer cells.

Four test tubes with open caps in a blue rack; liquid is being poured into one tube.
Research
February 9, 2017 • 2 Min

Testing Standard Treatment Plus an Antibody to Shrink Pancreatic Tumors

Researchers are testing whether adding a monoclonal antibody to standard chemotherapy will make locally advanced pancreatic cancer qualify for surgery.

Image of a yellow and gold metal circle with wires across the center, in an abstract geometic pattern.
Research
January 27, 2017 • 2 Min

Electrical Pulses to Destroy Pancreatic Cancer Cells

A clinical trial looks the effectiveness of NanoKnife surgery on pancreatic cancer tumors that cannot be removed by traditional surgery.

Pancreas cross section embedded in paraffin wax, stained blue and purple, 100x magnification.
Research
January 16, 2017 • 2 Min

Comparing a Standard Chemotherapy With and Without a PARP Inhibitor

A clinical trial compares standard chemotherapy with and without the addition of a PARP inihibitor, for patients whose pancreatic cancer is spreading again.

against a dark blue background, transparent tubes in orange, lighter blue, red, and clear, indicate different aspects of cell transport. The image was created through an electron microscope.
Research
December 22, 2016 • 2 Min

A New Approach to Treating Some Advanced Pancreatic Cancer Patients

A clinical trial uses PEGPH20, a synthetic form of a human enzyme, to make treatment more effective in pancreatic cancer patients with high tumor pressure.

Abstract black and white image of laboratory equipment and tubes
Research
December 9, 2016 • 2 Min

Muting Chemical Signals to Slow or Stop the Spread of Pancreatic Cancer

A clinical trial tests a drug that turns off chemical signals in the body that promote the growth of tumors and the spread of pancreatic cancer.