Evaluating Different Immunotherapy Combinations
A platform clinical trial evaluates immunotherapy combinations with standard of care treatment for advanced pancreatic cancer.
Claudin May Be the Next Big Target in Pancreatic Cancer Treatment
While immunotherapy and other targeted treatments involving monoclonal antibodies have been successful in other cancers, pancreatic cancer has been notoriously tough to target because of a lack of suitable cell surface targets to which the antibodies can bind. But a new target has been identified, and researchers are hopeful that an investigational drug that homes…
Using Molecular Tumor Profiling to Determine the Best Pancreatic Cancer Treatment
A clinical trial looks at whether molecular subtyping of tumors is effective in determining the best pancreatic cancer treatment.
Finding More Clues about Circulating Tumor DNA
Researcher Dr. Gehan Botrus looks at circulating tumor DNA for genetic information on a patient’s pancreatic cancer to personalize treatment.
The Importance of a Good Treatment Team
Wayne Mullis credits his treatment team with choosing the best pancreatic cancer treatment for him and for helping him through treatment.
Disappointing Results of a Phase II Trial Using Angiogenesis Inhibitor
That’s the question researchers hoped to answer in a phase II double-blind trial comparing mFOLFIRINOX plus ramucirumab versus mFOLFIRINOX plus placebo in advanced pancreatic cancer patients. Results of the trial were presented at the 2021 ASCO GI Cancer Symposium. Ramucirumab is a monoclonal antibody that attaches to and inhibits a molecule called VEGFR-2, a vascular…
Researching More Second-Line Options for Pancreatic Cancer
Dr. Allyson Ocean explains the concept behind a novel second-line treatment being tested for metatstatic pancreatic cancer.
New Trial to Find Biomarkers to Guide Treatment
Drs. Jennifer Knox and Elizabeth Jaffee lead the PASS-01 trial using biomarkers and other measures to choose individualized treatment.
The Pancreatic Standard of Care is No Longer So Standard
Do you want to understand more about how your doctor chooses your treatments? Learn about the standard of care for pancreatic cancer.
Adding Focused Radiation to Standard Pancreatic Cancer Treatment
Researchers are using IORT–intraoperative radiation therapy–to treat pancreatic cancer that cannot be surgically removed.