Family History

411 articles

Research
July 26, 2016 • 2 Min

Maintenance Chemotherapy Trial for Pancreatic Cancer Patients with the BRCA Mutation

A clinical trial for patients with BRCA mutations uses a PARP inhibitor as part of the maintenance chemotherapy experimental treatment.

Research
December 5, 2017 • 5 Min

The ABCs of Genetic Testing

There are a number of different genetic mutations that can cause familial pancreatic cancer. This article explains some of the most common ones.

Survivor Stories
March 15, 2024 • 4 Min

Sometimes Things Get Worse Before They Get Better

Matthew Rosenblum thought his time was limited after a pancreatic cancer diagnosis at age 32, but he’s a BRCA2 carrier, which opened treatment options.

Survivor Stories
March 31, 2020 • 5 Min

Strong Like a Dinosaur

Diagnosed with pancreatic cancer on her 40th birthday, Andrea Barkstrom receives chemotherapy and is living up to her motto: Strong Like a Dinosaur.

Research
June 27, 2017 • 2 Min

A Maintenance Trial for Patients with BRCA or PALB2 Mutations

A clinical trial examines whether the PARP inhibitor rucaparib can work as a maintenance drug for pancreatic cancer patients with BRCA or PALB2 mutations.

Research
May 25, 2021 • 2 Min

PARP Inhibitor as Maintenance for Pancreatic Cancer Patients with BRCA1, BRCA2, or PALB2 Mutations

A new clinical trial tests a PARP inhibitor as maintenance treatment for pancreatic cancer patients with BRCA1/2 or PALB2 mutations.

Research
November 8, 2016 • 4 Min

BRCA’s Role in Pancreatic Cancer Investigated

The relationship between BRCA and pancreatic cancer, and how that affects treatment, is the focus of clinical trials looking at PARP inhibitors.

Research
March 26, 2019 • 4 Min

Damage as a Way to Repair Pancreatic Cancer

Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.

Survivor Stories
August 6, 2024 • 4 Min

Lucky to Find It Early

When Jeneen Genna did not feel well her doctor searched until they found pancreatic cancer. The BRCA2 mutation has her in a clinical trial.

Research
September 30, 2016 • 4 Min

Pancreatic Cancer Tissue Helps Unlock the Disease’s Secrets

Dr. Christine Iacobuzio-Donahue at Memorial Sloan Kettering is using techniques from evolutionary biology to learn how pancreatic cancer grows.

Survivor Stories
April 4, 2016 • 3 Min

Personalized Treatment Plans in the Fight Against PC

David Dessert explains that his aunt’s genetic testing for BRCA2 mutation directed his own treatment for pancreatic cancer.

Survivor Stories
April 24, 2020 • 5 Min

Genetic Testing Leads Me to a PARP Inhibitor Trial

Harvey Parker had genetic testing as part of his initial pancreatic cancer treatment. The BRCA2 mutation led him to a PARP inhibitor clinical trial.

Survivor Stories
March 8, 2019 • 5 Min

Facing Pancreatic Cancer and Making the Most of Borrowed Time

With a young family, Justin Baker is hoping for more time because he has a genetic mutation that favors certain treatments.

Survivor Stories
November 20, 2019 • 6 Min

Tumor RNA Testing Leads to Treatment with a New Drug

When treatment stopped working for Adam Deal, genetic testing of his tumor RNA found a mutation that made him eligible to try a new drug.

Survivor Stories
September 23, 2021 • 5 Min

The Butterfly Effect and Living Every Day to My Fullest

Because Helene Avraham-Katz has the BRCA2 mutation, certain chemotherapies work better and she is eligible for specific clinical trials.