genetic familial mutations

492 articles

Research
June 19, 2023 • 7 Min

Progress in BRCA-Related Cancers Highlighted By the Basser Center

The Basser Center for BRCA hosted a panel discussion of the latest breakthroughs and discoveries for BRCA-related cancers.

Research
February 4, 2019 • 5 Min

Genetic Testing for All Pancreatic Cancer Patients

A study by Dr. Gloria Petersen’s research team has led to an official recommendation that all pancreatic cancer patients get genetic testing.

Research
June 2, 2017 • 2 Min

Focusing on a Drug that Treats Specific Tumor Mutations

A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.

Treatments
December 21, 2020 • 5 Min

This Versus That: Words to Know

Confused about some of the similar-sounding terms you are hearing during pancreatic cancer treatment? Our list of words to know can help.

Research
November 1, 2018 • 5 Min

PARP Inhibitors for Pancreatic Cancer Maintenance Treatment

Dr. Kim Reiss Binder is leading a clinical trial of maintenance treatment with the PARP inhibitor rucaparib, for patients who carry the BRCA mutation.

Research
April 5, 2018 • 4 Min

Genetic Testing Can Help Those You Love

Dr. Fay Kastrinos, director of the Muzzi Mirza Pancreatic Cancer Prevention and Genetics Program at Columbia University Medical Center, explains the value of genetic testing for cancer prevention and treatment.

Research
July 5, 2018 • 4 Min

A Potential Role for PARP Inhibitors in Pancreatic Cancer

Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.

Page
June 20, 2022 • 1 Min

Glossary

Our extensive collection of web-based and other resources for patients, families, and caregivers provides easy access to information on a wide variety of subjects related to pancreatic cancer.

Research
November 8, 2016 • 4 Min

BRCA’s Role in Pancreatic Cancer Investigated

The relationship between BRCA and pancreatic cancer, and how that affects treatment, is the focus of clinical trials looking at PARP inhibitors.

Research
November 12, 2019 • 6 Min

Using Tumor Tissue Samples to Break Down Assumptions About Pancreatic Cancer

Dr. Christine Iacobuzio-Donahue uses tumor tissue samples to study how pancreatic cancer tumors develop, so she can find ways to stop the disease.

Research
February 9, 2023 • 5 Min

PRECEDE Trial Sets Survival Rate Goal

Dr. Raymond Wadlow explains how earlier detection of high-risk people is key the PRECEDE trial’s goal to increase pancreatic cancer survival rates.

Research
June 27, 2017 • 2 Min

A Maintenance Trial for Patients with BRCA or PALB2 Mutations

A clinical trial examines whether the PARP inhibitor rucaparib can work as a maintenance drug for pancreatic cancer patients with BRCA or PALB2 mutations.

Research
January 9, 2019 • 6 Min

Pancreatic Cancer: 2018 Highlights And Looking Forward to 2019

Dr. Allyson Ocean leads an overview of the new treatments and protocol from 2018 as well as what are the next steps in treatment for 2019.

Survivor Stories
October 9, 2024 • 6 Min

Genetic Testing Guided My Treatment Plan

Ryan Dwars already knew there was pancreatic cancer in his family so when he was diagnosed he asked for genetic testing right away.

Research
July 27, 2017 • 4 Min

Most Cancer Mutations Are Random DNA Mistakes

In a large study, Dr. Bert Vogelstein of Johns Hopkins found that a majority of cancers, including pancreatic cancer, are caused by random mutations of DNA.