Genetic Mutations

391 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Research
March 26, 2020 • 2 Min

Combining Two Drugs with Different Approaches to Enhance Treatment

A clinical trial combines epigenetic therapy and immunotherapy to make immunotherapy more effective for patients with pancreatic and bile duct cancers.

Research
August 14, 2024 • 5 Min

Early Study Shows Exercise Alone Can Reduce Inflammation

Dr. Zobeida Cruz-Monserrate is studying how exercise can reduce inflammation, and how that impacts pancreatic cancer.

Research
June 1, 2016 • 5 Min

Personalizing Pancreatic Cancer Treatment

Dr. Mark Ricigliano takes a closer look at the genetics of circulating tumor cells, to personalize pancreatic cancer treatment for the best results.

Disease Management
November 10, 2023 • 6 Min

Why Clinical Trials Should Be a Patient’s Starting Point

Why are clinical trials such an important part of pancreatic cancer treatment? We outline many reasons doctors and patients should look at trials.

Research
May 10, 2024 • 6 Min

Using AI to Create a Better Test to Predict Pancreatic Cancer Progression

Dr. Dan Theodorescu is using AI to isolate more effective biomarkers than the CA 19-9 test to track pancreatic cancer progression.

Research
October 25, 2024 • 10 Min

Research: The Next Generation

AACR young researchers come from all over the world, and add their perspectives to pancreatic cancer studies.

Page
November 12, 2024 • 1 Min

Risks and Symptoms

Survivor Stories
June 13, 2018 • 7 Min

Aiming to be More than a Statistic

Dr. Paul Silverstein knew that he needed genomic testing, immunotherapy, and a clinical trial in his battle with pancreatic cancer.

Survivor Stories
December 7, 2018 • 3 Min

The Positive Impact of a Pancreatic Cancer Clinical Trial

Richard Blish was a healthy, athletic 67-year-old when he developed symptoms of pancreatic cancer. His daughter steered him to a clinical trial for treatment.

Research
January 16, 2017 • 2 Min

Comparing a Standard Chemotherapy With and Without a PARP Inhibitor

A clinical trial compares standard chemotherapy with and without the addition of a PARP inihibitor, for patients whose pancreatic cancer is spreading again.

Research
July 28, 2016 • 6 Min

Novel Drug Therapy Kills Pancreatic Cancer Cells by Reducing Levels of Antioxidants

New research finds that reducing antioxidants can help kill pancreatic cancer cells, suggesting a new direction for treatment.

Research
March 23, 2020 • 6 Min

Challenge Grant Recipients Moving Forward

The Pancreatic Cancer Collective awarded four teams a second round of New Therapies Challenge Grants, to further develop new pancreatic cancer treatment.

Research
April 24, 2023 • 9 Min

Research and Other Highlights from the 2023 AACR Annual Meeting

The 2023 AACR meeting focused on the latest research into KRAS, other immunotherapy approaches, and honored Dr. Elizabeth Jaffee.

Advocacy
January 4, 2022 • 5 Min

Steven Merlin and Davi D’Agostino Team Up to Help Others

Pancreatic cancer patient advocates Steven Merlin and Davi D’Agostino have joined to pool expertise and information for other patients.

Survivor Stories
July 13, 2018 • 6 Min

A Longer Plan with Treatment Options

Susan Riddle had chemotherapy and radiation before she qualified for NanoKnife treatment, all to control her pancreatic cancer.