Research

What research is being done for pancreatic cancer treatments and screenings today? The next life-saving treatment for the disease may be on the horizon. These articles highlight the latest in pancreatic cancer research.

337 Articles

Clear glass beakers from above
Research
September 5, 2017 • 4 Min

New Cancer Stem Cell Pathway Drug May Change Standard of Care

Dr. Tanios Bekaii-Saab is testing a new drug that works on pancreatic cancer stem cells to make chemotherapy more effective.

Microscope slide of the pancreas, with the some structures in purple and some in pink
Research
August 30, 2017 • 2 Min

More Effective Focused Radiation Therapy and Chemotherapy for Locally Advanced Pancreatic Cancer

A clinical trial tests whether adding Zometa makes chemotherapy and stereotactic body radiation therapy (SBRT) more effective against pancreatic cancer.

Researcher Ken Zaret
Research
August 22, 2017 • 4 Min

A Newly Identified Biomarker Panel Shows Promise in Earlier Pancreatic Cancer Detection

The first pancreatic cancer blood test may soon be a reality, as a biomarker panel from the lab of Dr. Ken Zaret shows promise in early testing.

Photo of pill capsules with blue and beige ones in focus in the front, and out of focus pills in brown, pink and brown, and blue and beige in the background
Research
August 17, 2017 • 2 Min

Presurgical Treatment for Pancreatic Cancer That Is Removable

A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.

Dr. Bert Vogelstein
Research
July 27, 2017 • 4 Min

Most Cancer Mutations Are Random DNA Mistakes

In a large study, Dr. Bert Vogelstein of Johns Hopkins found that a majority of cancers, including pancreatic cancer, are caused by random mutations of DNA.

Magnified slide of human pancreas cells, stained in aqua color with a dark outline around some of the rounded cells
Research
July 24, 2017 • 2 Min

Trying a New Type of Treatment to Stop Advanced Pancreatic Cancer

Researchers test the chemotherapy combination of AM0010 and FOLFOX as a second-line therapy for people with metastatic pancreatic cancer.

Dr. Luis Diaz
Research
July 14, 2017 • 5 Min

An Immunotherapy Game Changer

Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.

Glass flasks with wider bottoms and narrower tops sit on a table; the left flask is partway filled with dark green clear liquid, the right flask contains a lighter bright green clear liquid
Research
July 11, 2017 • 2 Min

Testing the Safety of a New Chemotherapy and Radiation Combination

A clinical trial tests the effectiveness of adding PEGPH20 to standard chemotherapy and radiation in patients with locally advanced pancreatic cancer.

Petri dishes
Research
July 3, 2017 • 3 Min

Predicting Effective Therapy in Pancreatic Cancer

Dr. Kenneth Yu is leading a clinical trial that looks at a pancreatic cancer patient’s pharmacogenomic profile, to see which chemotherapy works better.

Illustration of a protein that includes the BRCA2 mutation. The illustration includes spirals in brown, strands in purple, blue directional arrows, and green, yellow, red, and blue circles.
Research
June 27, 2017 • 2 Min

A Maintenance Trial for Patients with BRCA or PALB2 Mutations

A clinical trial examines whether the PARP inhibitor rucaparib can work as a maintenance drug for pancreatic cancer patients with BRCA or PALB2 mutations.

Dr. Margaret Tempero
Research
June 23, 2017 • 4 Min

Targeted Therapy for Pancreatic Cancer

Dr. Margaret Tempero outlines the work being done in the area of targeted therapy for pancreatic cancer, specifically the testing of ibrutinib.

abstract image of stem cells with a large area of red, interspersed with blue, and bright green areas at the bottom of the image
Research
June 15, 2017 • 2 Min

Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer

A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.

Dr. Joseph Herman
Research
June 7, 2017 • 5 Min

Stereotactic Body Radiation Therapy (SBRT) for Select Pancreatic Cancer Patients

Stereotactic body radiation therapy (SBRT) is increasingly being used to treat locally advanced pancreatic cancer, and make it surgically removable.

Image of DNA analysis showing a series of darker and lighter orange-colored columns with thin horizontal red, yellow, white, and orange stripes indicating different genes
Research
June 2, 2017 • 2 Min

Focusing on a Drug that Treats Specific Tumor Mutations

A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.

Microscope image of periodontal bacteria
Research
May 26, 2017 • 4 Min

Periodontal Disease and Pancreatic Cancer?

Did you know that periodontal disease may predict pancreatic cancer? Researchers are finding a link between unhealthy gums and the deadly cancer.