Research
What research is being done for pancreatic cancer treatments and screenings today? The next life-saving treatment for the disease may be on the horizon. These articles highlight the latest in pancreatic cancer research.
347 Articles
![Magnified slide of human pancreas cells, stained in aqua color with a dark outline around some of the rounded cells](https://letswinpc.org/wp-content/uploads/2022/09/ct2017jul24.jpg)
Trying a New Type of Treatment to Stop Advanced Pancreatic Cancer
Researchers test the chemotherapy combination of AM0010 and FOLFOX as a second-line therapy for people with metastatic pancreatic cancer.
![Dr. Luis Diaz](https://letswinpc.org/wp-content/uploads/2017/07/Diaz-Head-v2.jpg)
An Immunotherapy Game Changer
Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.
![Glass flasks with wider bottoms and narrower tops sit on a table; the left flask is partway filled with dark green clear liquid, the right flask contains a lighter bright green clear liquid](https://letswinpc.org/wp-content/uploads/2022/09/ct2017jul11.jpg)
Testing the Safety of a New Chemotherapy and Radiation Combination
A clinical trial tests the effectiveness of adding PEGPH20 to standard chemotherapy and radiation in patients with locally advanced pancreatic cancer.
![Petri dishes](https://letswinpc.org/wp-content/uploads/2022/10/Petri-dishes.jpg)
Predicting Effective Therapy in Pancreatic Cancer
Dr. Kenneth Yu is leading a clinical trial that looks at a pancreatic cancer patient’s pharmacogenomic profile, to see which chemotherapy works better.
![Illustration of a protein that includes the BRCA2 mutation. The illustration includes spirals in brown, strands in purple, blue directional arrows, and green, yellow, red, and blue circles.](https://letswinpc.org/wp-content/uploads/2022/09/ct2017jun27.jpg)
A Maintenance Trial for Patients with BRCA or PALB2 Mutations
A clinical trial examines whether the PARP inhibitor rucaparib can work as a maintenance drug for pancreatic cancer patients with BRCA or PALB2 mutations.
![Dr. Margaret Tempero](https://letswinpc.org/wp-content/uploads/2022/10/Tempero2015-Newsletter.jpg)
Targeted Therapy for Pancreatic Cancer
Dr. Margaret Tempero outlines the work being done in the area of targeted therapy for pancreatic cancer, specifically the testing of ibrutinib.
![abstract image of stem cells with a large area of red, interspersed with blue, and bright green areas at the bottom of the image](https://letswinpc.org/wp-content/uploads/2022/09/ct2017jun15.jpg)
Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer
A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.
![Dr. Joseph Herman](https://letswinpc.org/wp-content/uploads/2017/06/Dr-Herman-v2.jpg)
Stereotactic Body Radiation Therapy (SBRT) for Select Pancreatic Cancer Patients
Stereotactic body radiation therapy (SBRT) is increasingly being used to treat locally advanced pancreatic cancer, and make it surgically removable.
![Image of DNA analysis showing a series of darker and lighter orange-colored columns with thin horizontal red, yellow, white, and orange stripes indicating different genes](https://letswinpc.org/wp-content/uploads/2022/09/ct2017jun2.jpg)
Focusing on a Drug that Treats Specific Tumor Mutations
A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.
![Microscope image of periodontal bacteria](https://letswinpc.org/wp-content/uploads/2022/10/periodontal-bacteria.jpg)
Periodontal Disease and Pancreatic Cancer?
Did you know that periodontal disease may predict pancreatic cancer? Researchers are finding a link between unhealthy gums and the deadly cancer.
![rack of test tubes](https://letswinpc.org/wp-content/uploads/2022/10/vessels-e1494552844232.jpg)
Synergy with Metronomic Chemotherapy
Oncologists are trying metronomic chemotherapy, lower doses of toxic drugs given on a steady basis, to fight pancreatic cancer.
![A paper model of DNA to illustrate genetic testing](https://letswinpc.org/wp-content/uploads/2022/09/ct2017may9.jpg)
Treating BRCA-Negative Pancreatic Cancer Patients with a Family Cancer History Similar to BRCA Carriers
A clinical trial looks at the effectiveness of a PARP inhibitor in BRCA-negative pancreatic cancer patients with a family history BRCA-type cancers.
![Microscope image of pancreatic cells in purple and teal on a dark background](https://letswinpc.org/wp-content/uploads/2022/09/ct2017apr18.jpg)
Testing a Signal-Inhibiting Drug on Tumors with Specific Mutations
A new drug for certain tumor mutations is being tested in a type of clinical trial called a basket trial, which matches tumor genetics and drugs.
![Microscope image of vitamin C crystals](https://letswinpc.org/wp-content/uploads/2022/10/Vitamin-c-Wellcome-images.jpg)
Testing Vitamin C as a Cancer Killer
Lewis Cantley’s team is starting clinical trials of vitamin C to gain more information about its role in stopping cancer.
![Black and white photo of clear plastic disks stacked randomly](https://letswinpc.org/wp-content/uploads/2022/09/ct2017apr5.jpg)
Comparing Chemotherapy and Radiation Regimens to Prevent Recurrence of Pancreatic Cancer
A clinical trial compares standard chemotherapy with gemcitabine to the combination of chemotherapy with capecitabine and radiation.