Research

What research is being done for pancreatic cancer treatments and screenings today? The next life-saving treatment for the disease may be on the horizon. These articles highlight the latest in pancreatic cancer research.

362 Articles

Dr. Alok Khorana
Research
July 31, 2018 • 4 Min

A Combination of Neoadjuvant Chemotherapy and Radiation Shows Promise

Dr. Alok Khorana discusses the results of clinical trials of neoadjuvant chemotherapy and radiation to make surgery more effective.

orange colored clear vitamin D pills in a circle against an orange background
Research
July 23, 2018 • 2 Min

A New Combination Chemotherapy Before Surgery

A new clinical trial adds vitamin D to standard of care chemotherapy before surgery, to make pancreatic cancer tumors more removable.

rounded tops of lab tubes
Research
July 18, 2018 • 3 Min

Adjuvant Chemotherapy with Modified FOLFIRINOX Regimen Improves Survival

A French clinical trial showed that adjuvant chemotherapy (given after surgery) with modified FOLFIRINOX improves survival of pancreatic cancer patients.

Draining board
Research
July 5, 2018 • 4 Min

A Potential Role for PARP Inhibitors in Pancreatic Cancer

Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.

DNA art built with wire and rainbow clear plastic
Research
June 26, 2018 • 2 Min

Early Detection Trial for People at Higher Risk of Pancreatic Cancer

Relatives of pancreatic cancer patients or people who carry certain mutations can participate in an early detection clinical trial.

water running into beaker
Research
June 21, 2018 • 3 Min

Multicenter Trial Focuses on Neoadjuvant Treatment for Borderline Resectable and Locally Advanced Disease

Dr. David Ryan outlines a new trial for pre-surgical pancreatic cancer treatment combining a blood pressure drug, immunotherapy, standard care and SBRT.

Black and white photo of test tubes upright in a rack
Research
June 13, 2018 • 2 Min

Testing the Effectiveness of Immunotherapy Added to a New Drug Combination

Researchers are testing a drug combination that adds immunotherapy to standard drugs used to treat pancreatic cancer and an antimalarial drug.

Tiny beams of X-ray radiation are generated using an array of carbon nanotube X-ray sources to deliver tumor-killing radiation, while preserving normal tissue; this micrograph shows a 250 micron wide section of tissue damage.
Research
May 31, 2018 • 2 Min

Finding the Best Dose of Radiation and an Experimental Drug

A clinical trial looks for the best dose of an experimental drug to combat the mouth sores that are a side effect of stereotactic body radiation therapy.

organoid under the microscope
Research
May 25, 2018 • 4 Min

The Promise of Organoids

Dr. Brian Wolpin explains how organoids are being used to develop personalized treatment for pancreatic cancer patients.

Researcher Douglas Fearon
Research
May 14, 2018 • 3 Min

Immunology Researchers Solve a Mystery of Metastasis

Physician and researcher Douglas Fearon and his lab have a possible explanation for how cancer cells metastasize, and the role surgery may play in this process.

metal balls connected with thin sticks on a purple and white background
Research
May 4, 2018 • 2 Min

Testing Immunotherapy for Safety Before and After Pancreatic Cancer Removal

Researchers are testing a new monoclonal antibody to see if it helps patients with pancreatic tumors that can be surgically removed.

Particle based vaccines
Research
May 1, 2018 • 3 Min

Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1

Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.

Cells from Dan course crop
Research
April 18, 2018 • 6 Min

Targeting Cancer Metabolism

Researchers from Tyme Technologies are focusing on cancer cell metabolism, particularly tyrosine, as a way to kill cancer cells.

Very high magnification of a pancreatic neuroendocrine tumor in a microscope
Clinical Trials
April 10, 2018 • 2 Min

Testing a New Drug on Advanced Pancreatic Neuroendocrine Tumors

In a clinical trial, the new drug sapanisertib is being tested for its effectiveness against pancreatic neuroendocrine tumors (PNETs).

Looking down a spiral staircase
Research
April 5, 2018 • 4 Min

Genetic Testing Can Help Those You Love

Dr. Fay Kastrinos, director of the Muzzi Mirza Pancreatic Cancer Prevention and Genetics Program at Columbia University Medical Center, explains the value of genetic testing for cancer prevention and treatment.