Completed Trials

57 Articles

Fractal flame ribbons in whte and red on a black background
Completed Trials
May 15, 2020 • 2 Min

Targeted Therapy to Inhibit Connective Tissue Growth in Pancreatic Cancer

Researchers are testing a new antibody, a type of targeted therapy, in combination with standard treatment for pancreatic cancer in a phase III trial.

Test tubes in a gold test tube holder
Completed Trials
April 21, 2020 • 2 Min

Testing a Drug that Works Only in the Tumor Microenvironment

Scientists are trying a new type of drug combination that gets activated only in the unique conditions of the tumor microenvironment.

The tops of closed lab vials as seen from overhead against a blue-ish background
Completed Trials
March 26, 2020 • 2 Min

Combining Two Drugs with Different Approaches to Enhance Treatment

A clinical trial combines epigenetic therapy and immunotherapy to make immunotherapy more effective for patients with pancreatic and bile duct cancers.

Killer T cells
Completed Trials
September 10, 2019 • 4 Min

CAR T Cell Trial Targets Mesothelin

In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.

microscope image of the structure of blood vessel endothelium with the proteins that hold the shapes in red
Completed Trials
June 14, 2019 • 2 Min

Testing a New Drug to Attack Pancreatic Tumor Blood Vessels

A clinical trial is testing a new drug combination that damages the tumor blood vessels and allows chemotherapy drugs to enter the tumor.

Precancerous pancreatic cells in mice
Completed Trials
May 20, 2019 • 2 Min

A New Drug to Target Cancer Cell Enzymes

Researchers are testing a drug that targets the enzymes that help generate energy for cell division, to disrupt pancreatic cancer cell multiplication.

multicolor abstract computer created image of series of squares that look like a DNA helix
Completed Trials
February 7, 2019 • 2 Min

Testing a Different Approach to Pancreatic Cancer Treatment

A drug that is epigenetic therapy, which alters how DNA behaves, is being tested in a clinical trial for pancreatic cancer.

black disc in motion against a yellow background
Completed Trials
December 12, 2018 • 2 Min

Electric Fields to Enhance Pancreatic Cancer Chemotherapy

A clinical trial uses electric fields to help slow the growth of tumor cells, In a clinical trial for pancreatic cancer patients.

Grayscale image of round lab containers with dark agar medium arranged in rows.
Completed Trials
October 16, 2018 • 2 Min

Finding a Safe Dose of a New Drug for Some Types of Solid Tumors

LMB-100 is a lab-created protein that targets mesothelin. It is being tested against pancreatic cancer and other solid tumors in a clinical trial.

laboratory glassware
Completed Trials
September 12, 2018 • 3 Min

Tough Tortoise of a Drug Beating Metastatic Pancreatic Cancer

Rexahn Pharmaceuticals is testing RX-3117, a slow-releasing drug similar to gemcitabine, in a clinical trial for metastatic pancreatic cancer patients.

White net mask in close up
Completed Trials
August 29, 2018 • 2 Min

Radiotherapy Implant plus Standard Chemotherapy

The OncoSil radiotherapy implant device is being tested on pancreatic cancer in a clinical trial that combines it with standard chemotherapy.

looking down on top of culture test tubes with red tops, against a light blue background
Completed Trials
August 3, 2018 • 2 Min

Targeting Tumor Proteins Specific to Pancreatic Cancer Cells

A clinical trial tests the safety and effectiveness of tumor-associated antigen-specific cytotoxic T lymphocytes, which target specific tumor proteins.

Very high magnification of a pancreatic neuroendocrine tumor in a microscope
Completed Trials
April 10, 2018 • 2 Min

Testing a New Drug on Advanced Pancreatic Neuroendocrine Tumors

In a clinical trial, the new drug sapanisertib is being tested for its effectiveness against pancreatic neuroendocrine tumors (PNETs).

microscope slide of blue dots in a pink and white background that make up a gastric inflammatory fibroid polyp
Completed Trials
February 22, 2018 • 3 Min

Helping Some Types of Chemotherapy Penetrate Pancreatic Tumors

A clinical trial looks at the effectiveness of PEGPH20 in helping chemotherapy penetrate the stroma of pancreatic tumors, to make them removable.

Abstract image of vertical ridged lines of reds and oranges
Completed Trials
January 24, 2018 • 2 Min

Chemoradiation Before Tumor Removal to Lessen Possible Post-Surgical Disease

A clinical trial examines the effectiveness of presurgical chemotherapy and radiation in making cancer-free margins after tumor removal.