phase I Archives - Let's Win! Pancreatic Cancer

DNA helix made of metal, plastic and stained glass

Drug Combination to Combat Pancreatic and other Gastrointestinal Cancers

Researchers are combining TAS-102, an approved drug for colorectal cancer, and nanoliposomal irinotecan, to see if they work on pancreatic and other gastrointestinal cancers.

image of a group of killer T cells (green and red) surrounding a cancer cell (blue, center).

CAR T Cell Trial Targets Mesothelin

In an immunotherapy clinical trial, Dr. Mark O'Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.

A yellow paper model of DNA helix against a dark background

Immunotherapy to Attack a Common Pancreatic Cancer Mutation

Researchers are testing a type of immunotherapy to attack a variant of the KRAS mutation; KRAS mutations occur in almost all pancreatic cancers.

Dr. Conan Kinsey, pancreatic cancer researcher, sitting in his office

Combination Delivers a Dual Punch to Pancreatic Cell Growth

Dr. Conan Kinsey outlines a clinical trial that has moved quickly from the lab to phase I, with a dual approach to delivering pancreatic cancer treatment.

A latex-gloved hand doing close lab work

Targeting Cancer-Associated Wasting With Experimental Immunotherapy

Wasting, or cachexia, is the focus of a clinical trial testing a cachexia immunotherapy treatment combined with standard pancreatic cancer treatment.

DNA helix made of multicolor dots on a bright blue background

Personalized Immunotherapy Vaccine for Pancreatic Cancer

Researchers are creating personalized vaccines to stimulate a pancreatic cancer patient's immune system after surgery and chemotherapy.

looking down on top of culture test tubes with red tops, against a light blue background

Targeting Tumor Proteins Specific to Pancreatic Cancer Cells

A clinical trial tests the safety and effectiveness of tumor-associated antigen-specific cytotoxic T lymphocytes, which target specific tumor proteins.

metal balls connected with thin sticks on a purple and white background

Testing Immunotherapy for Safety Before and After Pancreatic Cancer Removal

Researchers are testing a new monoclonal antibody to see if it helps patients with pancreatic tumors that can be surgically removed.

White and gray overlapping circles on a dark background

Testing a Breast Cancer Drug for Other Advanced Solid Tumors

In a clinical trial, a new class of breast cancer drug called a kinase inhibitor is being tested to treat pancreatic cancer.

Abstract image of DNA structure, with linked balls of greens on the left and reds and pinks on the right, forming a spiral net

New Drug for BRCA Carriers with Advanced Cancer

A phase I clinical trial is testing the effectiveness of a platinum-based drug for BRCA carriers with pancreatic, breast, and other cancers.