Blog

60 Articles

Particle based vaccines
Research
May 1, 2018 • 3 Min

Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1

Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.

microscope slide of blue dots in a pink and white background that make up a gastric inflammatory fibroid polyp
Research
February 22, 2018 • 2 Min

Helping Some Types of Chemotherapy Penetrate Pancreatic Tumors

A clinical trial looks at the effectiveness of PEGPH20 in helping chemotherapy penetrate the stroma of pancreatic tumors, to make them removable.

Photo of pill capsules with blue and beige ones in focus in the front, and out of focus pills in brown, pink and brown, and blue and beige in the background
Research
August 17, 2017 • 2 Min

Presurgical Treatment for Pancreatic Cancer That Is Removable

A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.

abstract image of stem cells with a large area of red, interspersed with blue, and bright green areas at the bottom of the image
Research
June 15, 2017 • 2 Min

Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer

A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.

Dr. Erkut Borazanci
Research
March 31, 2017 • 4 Min

Clinical Trial of Immunotherapy Plus Sunshine Vitamin May Help in Pancreatic Cancer Fight

Can vitamin D make it easier for chemotherapy drugs to reach the pancreatic cancer tumor? A clinical trial is testing this idea.

Microscope image of mouse pancreas duct cancer with different parts of the cells stained blue or red, against a dark background
Research
February 22, 2017 • 2 Min

Using a Virus to Infect and Destroy Pancreatic Cancer Cells

A clinical trial tests the combination of standard chemotherapy plus a common cold virus that has been modified to kill cancer cells.

Four test tubes with open caps in a blue rack; liquid is being poured into one tube.
Research
February 9, 2017 • 2 Min

Testing Standard Treatment Plus an Antibody to Shrink Pancreatic Tumors

Researchers are testing whether adding a monoclonal antibody to standard chemotherapy will make locally advanced pancreatic cancer qualify for surgery.

Close-up image of the top of a centrifuge, over the central axis
Research
January 2, 2017 • 2 Min

Testing Targeted Immunotherapy Against Pancreatic Cancer

Targeted immunotherapy is the focus of a clinical trial that tests the drug ibrutinib, approved for leukemia treatment, against pancreatic cancer.

against a dark blue background, transparent tubes in orange, lighter blue, red, and clear, indicate different aspects of cell transport. The image was created through an electron microscope.
Research
December 22, 2016 • 2 Min

A New Approach to Treating Some Advanced Pancreatic Cancer Patients

A clinical trial uses PEGPH20, a synthetic form of a human enzyme, to make treatment more effective in pancreatic cancer patients with high tumor pressure.

Abstract black and white image of laboratory equipment and tubes
Research
December 9, 2016 • 2 Min

Muting Chemical Signals to Slow or Stop the Spread of Pancreatic Cancer

A clinical trial tests a drug that turns off chemical signals in the body that promote the growth of tumors and the spread of pancreatic cancer.

Cancer researcher Sunil Hingorani
Research
September 19, 2016 • 4 Min

New Drug Shows Positive Results in Early Trials

A new drug called PEGPH20, which helps chemotherapy drugs reach their target, is showing positive results in an ongoing pancreatic cancer trial.

Microscope image of a yellow cell with white cells around it and partly reaching on it, on a teal background
Research
July 13, 2016 • 2 Min

Testing the Effect of a Malaria Drug on Standard Treatment

A clinical trial tests whether a malaria drug can make standard chemotherapy for advanced pancreatic cancer more effective.

microscope image of pancreatic cancer--the blue irregular circles on the left--and normal pancreas cells--the smaller circles on the right
Research
June 3, 2016 • 2 Min

Low-Dose Continuous Chemotherapy as Part of a New Combination of Drugs

A clinical trial uses a new immunotherapy drug in combination with standard chemotherapy drugs in metronomic therapy to treat metastatic pancreatic cancer.

Hand of a lab worker opening a petri dish and putting liquid in with a pipette, in yellow lighting
Research
June 1, 2016 • 5 Min

Personalizing Pancreatic Cancer Treatment

Dr. Mark Ricigliano takes a closer look at the genetics of circulating tumor cells, to personalize pancreatic cancer treatment for the best results.

microscope image of different cells in shades of green in a fluid
Research
April 5, 2016 • 2 Min

Combining Gene Therapy with Current First-line Treatments for Metastatic Pancreatic Cancer

Gene therapy combined with standard first-line chemotherapy treatment forms a clinical trial for metastatic pancreatic cancer.