Blog
60 Articles
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Helping Some Types of Chemotherapy Penetrate Pancreatic Tumors
A clinical trial looks at the effectiveness of PEGPH20 in helping chemotherapy penetrate the stroma of pancreatic tumors, to make them removable.
Presurgical Treatment for Pancreatic Cancer That Is Removable
A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.
Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer
A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.
Clinical Trial of Immunotherapy Plus Sunshine Vitamin May Help in Pancreatic Cancer Fight
Can vitamin D make it easier for chemotherapy drugs to reach the pancreatic cancer tumor? A clinical trial is testing this idea.
Using a Virus to Infect and Destroy Pancreatic Cancer Cells
A clinical trial tests the combination of standard chemotherapy plus a common cold virus that has been modified to kill cancer cells.
Testing Standard Treatment Plus an Antibody to Shrink Pancreatic Tumors
Researchers are testing whether adding a monoclonal antibody to standard chemotherapy will make locally advanced pancreatic cancer qualify for surgery.
Testing Targeted Immunotherapy Against Pancreatic Cancer
Targeted immunotherapy is the focus of a clinical trial that tests the drug ibrutinib, approved for leukemia treatment, against pancreatic cancer.
A New Approach to Treating Some Advanced Pancreatic Cancer Patients
A clinical trial uses PEGPH20, a synthetic form of a human enzyme, to make treatment more effective in pancreatic cancer patients with high tumor pressure.
Muting Chemical Signals to Slow or Stop the Spread of Pancreatic Cancer
A clinical trial tests a drug that turns off chemical signals in the body that promote the growth of tumors and the spread of pancreatic cancer.
Testing the Effect of a Malaria Drug on Standard Treatment
A clinical trial tests whether a malaria drug can make standard chemotherapy for advanced pancreatic cancer more effective.
Low-Dose Continuous Chemotherapy as Part of a New Combination of Drugs
A clinical trial uses a new immunotherapy drug in combination with standard chemotherapy drugs in metronomic therapy to treat metastatic pancreatic cancer.
Personalizing Pancreatic Cancer Treatment
Dr. Mark Ricigliano takes a closer look at the genetics of circulating tumor cells, to personalize pancreatic cancer treatment for the best results.
Combining Gene Therapy with Current First-line Treatments for Metastatic Pancreatic Cancer
Gene therapy combined with standard first-line chemotherapy treatment forms a clinical trial for metastatic pancreatic cancer.