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64 Articles

A New Combination Chemotherapy Before Surgery
A new clinical trial adds vitamin D to standard of care chemotherapy before surgery, to make pancreatic cancer tumors more removable.

Testing the Effectiveness of Immunotherapy Added to a New Drug Combination
Researchers are testing a drug combination that adds immunotherapy to standard drugs used to treat pancreatic cancer and an antimalarial drug.

Testing Immunotherapy for Safety Before and After Pancreatic Cancer Removal
Researchers are testing a new monoclonal antibody to see if it helps patients with pancreatic tumors that can be surgically removed.

Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.

Helping Some Types of Chemotherapy Penetrate Pancreatic Tumors
A clinical trial looks at the effectiveness of PEGPH20 in helping chemotherapy penetrate the stroma of pancreatic tumors, to make them removable.

Presurgical Treatment for Pancreatic Cancer That Is Removable
A clinical trial looks at immunotherapy plus vitamin D plus standard chemotherapy before surgery to remove pancreatic cancer.

Adding a New Drug to Standard Treatment for Metastatic Pancreatic Cancer
A clinical trial tests the effectiveness of napabucasin, a drug that affects the signaling pathways of cancer stem cells.

Clinical Trial of Immunotherapy Plus Sunshine Vitamin May Help in Pancreatic Cancer Fight
Can vitamin D make it easier for chemotherapy drugs to reach the pancreatic cancer tumor? A clinical trial is testing this idea.

Using a Virus to Infect and Destroy Pancreatic Cancer Cells
A clinical trial tests the combination of standard chemotherapy plus a common cold virus that has been modified to kill cancer cells.

Testing Standard Treatment Plus an Antibody to Shrink Pancreatic Tumors
Researchers are testing whether adding a monoclonal antibody to standard chemotherapy will make locally advanced pancreatic cancer qualify for surgery.

Testing Targeted Immunotherapy Against Pancreatic Cancer
Targeted immunotherapy is the focus of a clinical trial that tests the drug ibrutinib, approved for leukemia treatment, against pancreatic cancer.

A New Approach to Treating Some Advanced Pancreatic Cancer Patients
A clinical trial uses PEGPH20, a synthetic form of a human enzyme, to make treatment more effective in pancreatic cancer patients with high tumor pressure.

Muting Chemical Signals to Slow or Stop the Spread of Pancreatic Cancer
A clinical trial tests a drug that turns off chemical signals in the body that promote the growth of tumors and the spread of pancreatic cancer.