genetic familial mutations
498 articles
Eighteen Important Words to Know if You Have Pancreatic Cancer
When you start pancreatic cancer treatment it seems like everyone is speaking a language you don’t know. Here are 18 important words to help you along.
Tumor RNA Testing Leads to Treatment with a New Drug
When treatment stopped working for Adam Deal, genetic testing of his tumor RNA found a mutation that made him eligible to try a new drug.
Understanding Family History Makes a Difference in Treatment Options
Elizabeth Pršić describes her mother Andrea’s pancreatic cancer treatment. Andrea has the BRCA2 mutation, which helps determine the plan.
What Caused My Pancreatic Cancer?
Despite no known genetic link, Steven Robinson is the fourth member of his family on his mother’s side to get pancreatic cancer.
An Immunotherapy Game Changer
Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.
The Value of Molecular Profiling and Genetic Testing
Gina Harrison underwent molecular profiling of her pancreatic tumor, which led her to a clinical trial. Genetic testing showed her BRCA1 mutation was random.
Testing an Approved Drug for a Specific Mutation
Researchers are testing a drug combination for melanoma in pancreatic cancer patients with a BRAF genetic mutation.
New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors
A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.
Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer
Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.
No One Fights Alone
Because of her grandfather, Rhonda Havig knew she had a family history of pancreatic cancer. But her own diagnosis was still a surprise.
Study Reveals Molecular Differences in Young-Onset Pancreatic Cancer
There has been a notable increase in cases of young onset pancreatic cancer. Dr. Jashodeep Datta and team are exploring why this is happening.
Working With your Doctor to Find Clinical Trials
Oncologist Dr. Kim A. Reiss explains the importance of clinical trials and family history of cancer when choosing a treatment for pancreatic cancer.
The Impact of BRCA Is Broader Than Breast and Ovarian Cancer
Rona Greenberg discusses the impact of BRCA2 on her family, and her search for the best clinical trial for her needs after her pancreatic cancer diagnosis.
Facing Pancreatic Cancer and Making the Most of Borrowed Time
With a young family, Justin Baker is hoping for more time because he has a genetic mutation that favors certain treatments.
Younger Brother’s Pancreatic Cancer Leads to Regular Screening for his Oldest Brother
When Scott Nelson was diagnosed with pancreatic cancer, oldest brother Steve began regular screening, which lead to his early diagnosis.