genetic familial mutations
498 articles
Damage as a Way to Repair Pancreatic Cancer
Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.
CRISPR: A New Tool to Help Understand Cancer-Linked Mutations
Lukas Dow, Ph.D., is using CRISPR technology to find better ways to fight cancer by editing the genome.
Molecular Profiling: Getting to Know Your Tumor
Dr. Johanna Bendell explains the value of molecular profiling, which can indicate the best type of chemotherapy for your tumor.
Maintenance Chemotherapy Trial for Pancreatic Cancer Patients with the BRCA Mutation
A clinical trial for patients with BRCA mutations uses a PARP inhibitor as part of the maintenance chemotherapy experimental treatment.
Chemotherapy Plus Stem Cell Infusion and Vitamins for BRCA Mutated Pancreatic Cancer
A clinical trial for pancreatic cancer patients with a BRCA mutation uses a combination of chemotherapy, vitamins, and stem cells.
Representing Genetic and Clinical Diversity in Pancreatic Cancer
Dr. Kentaro Sudo explores the possible causes for different responses to drugs among ethnic groups, pointing to the need for clinical diversity in trials.
Genetic Testing and Molecular Profiling Can Guide Treatment
Watch our webinar on Genetic Testing and Molecular Profiling to learn from experts and patients why this is so important.
Cherishing the Simple Things
Elizabeth O’Connor has a PALB2 genetic mutation so her stage IV pancreatic cancer has responded to immunotherapy.
Taking Nothing For Granted
After Whipple surgery and chemoradiation, Susan Zbacnik had molecular profiling, genetic testing, and joined an Immunotherapy clinical trial.
Meet the Researcher: Nicolette Juliana Rodriguez, M.D., M.P.H.
Learn more about the research interests of Nicolette Rodriguez, M.D., M.P.H., one of the young investigators Let’s Win sponsored at AACR.
Treating BRCA-Negative Pancreatic Cancer Patients with a Family Cancer History Similar to BRCA Carriers
A clinical trial looks at the effectiveness of a PARP inhibitor in BRCA-negative pancreatic cancer patients with a family history BRCA-type cancers.
Genetic Testing Changed My Chemo Protocol
Greg Jacobson’s family has an extensive history of cancer. After a pancreatic cancer diagnosis, genetic testing found the mutation for Lynch syndrome.
Pancreatic Cancer and Family History
Dr. Diane Simeone is developing a tablet-based family history survey to identify patients with a genetic-based risk for developing pancreatic cancer.
Pancreatic Cancer Caught Early Because of My Vigilance
Beverly Leighton joined a screening study and underwent genetic testing because of her family history of pancreatic cancer.
New Biopsy Shows Promise For Pancreatic Cancer Patients
Trovagene is developing a liquid biopsy for pancreatic cancer patients, to allow doctors to test for cancer and track treatment response.