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498 articles
An Update on the Whipple Procedure
Learn more about the latest developments in the Whipple procedure, the surgery most often used to remove pancreatic tumors.
Clinical Trial of Immunotherapy Plus Sunshine Vitamin May Help in Pancreatic Cancer Fight
Can vitamin D make it easier for chemotherapy drugs to reach the pancreatic cancer tumor? A clinical trial is testing this idea.
Synergy with Metronomic Chemotherapy
Oncologists are trying metronomic chemotherapy, lower doses of toxic drugs given on a steady basis, to fight pancreatic cancer.
Periodontal Disease and Pancreatic Cancer?
Did you know that periodontal disease may predict pancreatic cancer? Researchers are finding a link between unhealthy gums and the deadly cancer.
Targeted Therapy for Pancreatic Cancer
Dr. Margaret Tempero outlines the work being done in the area of targeted therapy for pancreatic cancer, specifically the testing of ibrutinib.
Predicting Effective Therapy in Pancreatic Cancer
Dr. Kenneth Yu is leading a clinical trial that looks at a pancreatic cancer patient’s pharmacogenomic profile, to see which chemotherapy works better.
Overcoming Challenges to Vaccine Immunotherapy
Dr. Elizabeth Jaffee explains the challenges facing the scientists developing vaccine-based immunotherapy for pancreatic cancer.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Targeting Cancer Metabolism
Researchers from Tyme Technologies are focusing on cancer cell metabolism, particularly tyrosine, as a way to kill cancer cells.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Immunology Researchers Solve a Mystery of Metastasis
Physician and researcher Douglas Fearon and his lab have a possible explanation for how cancer cells metastasize, and the role surgery may play in this process.
The Promise of Organoids
Dr. Brian Wolpin explains how organoids are being used to develop personalized treatment for pancreatic cancer patients.
Multicenter Trial Focuses on Neoadjuvant Treatment for Borderline Resectable and Locally Advanced Disease
Dr. David Ryan outlines a new trial for pre-surgical pancreatic cancer treatment combining a blood pressure drug, immunotherapy, standard care and SBRT.
Adjuvant Chemotherapy with Modified FOLFIRINOX Regimen Improves Survival
A French clinical trial showed that adjuvant chemotherapy (given after surgery) with modified FOLFIRINOX improves survival of pancreatic cancer patients.
Tough Tortoise of a Drug Beating Metastatic Pancreatic Cancer
Rexahn Pharmaceuticals is testing RX-3117, a slow-releasing drug similar to gemcitabine, in a clinical trial for metastatic pancreatic cancer patients.