drug combination
199 articles
Modifying the Tumor Microenvironment to Make Treatment More Effective
Researchers are testing a new drug that better-allows chemotherapy to penetrate the tumor microenvironment of pancreatic cancer.
Clinical Trial For OncoTreat Being Developed
Researcher Kenneth Olive is developing OncoTreat, a method matches a patient’s tumor to the most effective drugs for their pancreatic cancer.
Immunotherapy for Pancreatic Neuroendocrine Tumors
A clinical trial combines the immunotherapy drug pembrolizumab with lanreotide, a drug typically used to treat pancreatic neuroendocrine tumors.
Earlier Detection of Pancreatic Cancer: A Marathon, Not A Sprint
Dino Verrelli of Project Purple joins with Dr. Diane Simeone on the PRECEDE Consortium to develop earlier detection and new pancreatic cancer treatments.
Harnessing the Power of Radionuclide Therapy
Julie Sutcliffe is working with targeted radionuclide therapy to go after pancreatic cancer cells that have spread beyond the pancreas.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
Slowing the Growth of One Type of Advanced Neuroendocrine Tumor
Dr. Kelsey Klute explains the advantages of the radiopharmaceutical lutetium Lu 177 dotatate treatment for certain neuroendocrine tumors.
Exploring the Better Treatment for Stable Metastatic Pancreatic Cancer
For patients with stable metastatic pancreatic cancer, a clinical trial compares standard chemotherapy with immunotherapy.
Cracking the KRAS Code
Dr. Despina Siolas is focusing her research on new treatments for pancreatic cancer, particularly ones that go after KRAS mutations.
Representing Genetic and Clinical Diversity in Pancreatic Cancer
Dr. Kentaro Sudo explores the possible causes for different responses to drugs among ethnic groups, pointing to the need for clinical diversity in trials.
Testing the Effectiveness of Radiation and Standard Treatment
A clinical trial compares FOLFIRINOX plus stereotactic body radiation therapy (SBRT) with just FOLFIRINOX for pancreatic cancer that has spread locally.
MRI-Guided Radiation: A New Option for Pancreatic Cancer Treatment
Dr. Parag Parikh and others are using MRI-guided radiation to provide precision radiation treatment for pancreatic cancer.
For Pancreatic Cancer Patients, Pain Control Through Targeted Radiotherapy
Dr. Yaacov Lawrence is using celiac plexus radiotherapy in a clinical trials to target a source of pain for pancreatic cancer patients.
Newly Discovered Protein Complex in RAS Pathway May Provide a Treatment Target
Dr. Andrew Aguirre and other researchers from Dana-Farber and the Broad Institute are looking at the RAS pathway for a new target.
Maintenance Chemotherapy for Stable Metastatic Pancreatic Cancer
A clinical trial tests the diabetes drug metformin and transplant rejection preventative rapamycin to act as maintenance chemotherapy for pancreatic cancer.