Genetic Mutations and Family History
692 articles
Most Cancer Mutations Are Random DNA Mistakes
In a large study, Dr. Bert Vogelstein of Johns Hopkins found that a majority of cancers, including pancreatic cancer, are caused by random mutations of DNA.
Genetic Testing Leads Me to a PARP Inhibitor Trial
Harvey Parker had genetic testing as part of his initial pancreatic cancer treatment. The BRCA2 mutation led him to a PARP inhibitor clinical trial.
Working Hard to Beat Pancreatic Cancer
Sandy Robis underwent a full pancreatectomy and chemotherapy to help her beat pancreatic cancer. Now she helps support other patients.
Don’t Let Doctors Tell You Nothing’s Wrong
After a long road to diagnosis Brandon Stone learned he has a BRCA2 genetic mutation that impacts his treatment.
Meet the Researcher: Nicolette Juliana Rodriguez, M.D., M.P.H.
Learn more about the research interests of Nicolette Rodriguez, M.D., M.P.H., one of the young investigators Let’s Win sponsored at AACR.
Pancreatic Cancer: 2018 Highlights And Looking Forward to 2019
Dr. Allyson Ocean leads an overview of the new treatments and protocol from 2018 as well as what are the next steps in treatment for 2019.
New Study Aims to Reduce Recurrence Risk for Select Patients
Dr. Kim A. Reiss is leading a study of the PARP inhibitor olaparib to delay or prevent a recurrence of surgically removed pancreatic cancer.
This Versus That: Words to Know
Confused about some of the similar-sounding terms you are hearing during pancreatic cancer treatment? Our list of words to know can help.
A Genetic Mutation Aids My Treatment
Malcolm Robertson carries the BRCA2 mutation, so when he was diagnosed with pancreatic cancer, platinum-based chemo was part of his treatment.
Pancreatic Cancer Tissue Helps Unlock the Disease’s Secrets
Dr. Christine Iacobuzio-Donahue at Memorial Sloan Kettering is using techniques from evolutionary biology to learn how pancreatic cancer grows.
Platinum-Based Therapy Can Significantly Improve Survival for Some Pancreatic Cancer Patients
Dr. Michael Pishvaian explains how platinum-based therapy can improve the survival of pancreatic cancer patients with a specific mutation.
My BRCA2 Mutation Turned Out to Be Both the Curse and the Cure
Sharon Seibel knew she had the BRCA2 mutation but was unaware of the link to pancreatic cancer. Her chemotherapy was one for BRCA carriers.
Early Detection Makes All the Difference
Carolynn Kiel lost her mother and sister to pancreatic cancer. Regular screening allowed early detection of her pancreatic cancer.
Focusing on a Drug that Treats Specific Tumor Mutations
A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.
Damage as a Way to Repair Pancreatic Cancer
Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.