genetic familial mutations

492 articles

Survivor Stories
January 22, 2021 • 6 Min

What Caused My Pancreatic Cancer?

Despite no known genetic link, Steven Robinson is the fourth member of his family on his mother’s side to get pancreatic cancer.

Treatments
May 29, 2020 • 5 Min

Eighteen Important Words to Know if You Have Pancreatic Cancer

When you start pancreatic cancer treatment it seems like everyone is speaking a language you don’t know. Here are 18 important words to help you along.

Research
July 14, 2017 • 5 Min

An Immunotherapy Game Changer

Immunotherapy with Keytruda (pembrolizumab) is approved for use in cancer patients with certain genetic defects in their tumors.

Survivor Stories
August 18, 2020 • 4 Min

The Value of Molecular Profiling and Genetic Testing

Gina Harrison underwent molecular profiling of her pancreatic tumor, which led her to a clinical trial. Genetic testing showed her BRCA1 mutation was random.

Research
March 11, 2022 • 2 Min

Testing an Approved Drug for a Specific Mutation

Researchers are testing a drug combination for melanoma in pancreatic cancer patients with a BRAF genetic mutation.

Research
June 17, 2022 • 3 Min

New Gene Inhibitor Drug for Patients with MTAP-Deleted Tumors

A new trial targets patients with advanced solid tumors, including pancreatic cancer, with an MTAP-deletion genetic mutation.

Research
October 17, 2019 • 3 Min

Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer

Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.

Survivor Stories
June 1, 2023 • 4 Min

No One Fights Alone

Because of her grandfather, Rhonda Havig knew she had a family history of pancreatic cancer. But her own diagnosis was still a surprise.

Research
May 23, 2024 • 4 Min

Study Reveals Molecular Differences in Young-Onset Pancreatic Cancer

There has been a notable increase in cases of young onset pancreatic cancer. Dr. Jashodeep Datta and team are exploring why this is happening.

Survivor Stories
August 15, 2016 • 5 Min

The Impact of BRCA Is Broader Than Breast and Ovarian Cancer

Rona Greenberg discusses the impact of BRCA2 on her family, and her search for the best clinical trial for her needs after her pancreatic cancer diagnosis.

Survivor Stories
March 8, 2019 • 5 Min

Facing Pancreatic Cancer and Making the Most of Borrowed Time

With a young family, Justin Baker is hoping for more time because he has a genetic mutation that favors certain treatments.

Survivor Stories
June 6, 2019 • 5 Min

Younger Brother’s Pancreatic Cancer Leads to Regular Screening for his Oldest Brother

When Scott Nelson was diagnosed with pancreatic cancer, oldest brother Steve began regular screening, which lead to his early diagnosis.

Survivor Stories
October 9, 2023 • 3 Min

Changing Course Midstream

Barbara Green wasn’t happy with her doctors, so she took the advice of her support group, was an advocate for herself, and changed doctors.

Survivor Stories
March 15, 2024 • 4 Min

Sometimes Things Get Worse Before They Get Better

Matthew Rosenblum thought his time was limited after a pancreatic cancer diagnosis at age 32, but he’s a BRCA2 carrier, which opened treatment options.

Treatments
August 5, 2016 • 3 Min

Working With your Doctor to Find Clinical Trials

Oncologist Dr. Kim A. Reiss explains the importance of clinical trials and family history of cancer when choosing a treatment for pancreatic cancer.