Genetic Mutations

358 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Survivor Stories
June 14, 2022 • 5 Min

Go Live Your Life

After his pancreatic cancer diagnosis, Dean Jackson took his treatment of chemotherapy, radiation, and a Whipple procedure step by step.

Treatments
April 16, 2016 • 5 Min

Why You Need This Simple Blood Test at Diagnosis

An important factor in determining which treatment to use for pancreatic cancer patients is measuring the level of tumor marker CA-19-9. Learn more here.

Research
December 30, 2016 • 4 Min

The Cancer Moonshot

Dr. Elizabeth Jaffee of Johns Hopkins is part of the Cancer Moonshot’s Blue Ribbon Panel, and she explains the goals of the program.

Research
June 7, 2017 • 5 Min

Stereotactic Body Radiation Therapy (SBRT) for Select Pancreatic Cancer Patients

Stereotactic body radiation therapy (SBRT) is increasingly being used to treat locally advanced pancreatic cancer, and make it surgically removable.

Research
February 27, 2018 • 3 Min

Precision Medicine from the Get-Go for Pancreatic Cancer

Dr. Ben George and colleagues at the Medical College of Wisconsin are using molecular profiling to determine the best chemotherapy for a patient’s pancreatic cancer.

Research
March 12, 2018 • 5 Min

Making Surgery An Option for More Pancreatic Cancer Patients

Dr. John Chabot explains that more pancreatic cancer patients may qualify for surgery if they consult an experience pancreatic surgical team.

Research
August 13, 2018 • 5 Min

Man + Machine: Using Deep Learning for Early Detection of Pancreatic Cancer

Dr. Elliot Fishman is part of a team that is using artificial intelligence, or deep learning to develop techniques for early detection of pancreatic cancer.

Research
February 15, 2019 • 4 Min

Pancreatic Microbiome May Hold the Key To Better Treatment

Dr. Deirdre Cohen’s research into the pancreatic microbiome has found that gut bacteria may directly influence the effectiveness of immunotherapy.

Research
April 19, 2019 • 6 Min

New Clues in Pancreatic Cancer Weight Loss

Dr. Matthew Vander Heiden is researching how pancreatic tumors trigger weight loss in pancreatic cancer patients, and the relationship with survival.

Research
September 10, 2019 • 4 Min

CAR T Cell Trial Targets Mesothelin

In an immunotherapy clinical trial, Dr. Mark O’Hara is using CAR T cells to attack mesothelin-expressing tumor cells in pancreatic cancer.

Research
December 10, 2019 • 5 Min

Study Shows Fungi Boost Pancreatic Cancer Development and Growth

Drs. George Miller and Berk Aykut are leading research into the role of fungi in the growth and development of pancreatic cancer.

Survivor Stories
February 22, 2019 • 1 Min

Plenty to Live For

Steven was diagnosed with stage IV pancreatic cancer in 2012. Now a long-term survivor, he asked himself “What do I have to live for?” There was plenty.

Research
May 7, 2021 • 4 Min

Studying a New Approach for the Liquid Biopsy

Drs. Allyson Ocean and Ying-Hsiu Su lead a liquid biopsy pilot study looking for KRAS proteins in urine, to detect pancreatic cancer.

Research
August 19, 2021 • 5 Min

Large Phase III Global Trial Targets Cancer Metabolism

Dr. Philip Philip focuses on disrupting cancer cell metabolism with devimistat, now in a phase III global clinical trial.

Research
December 2, 2021 • 4 Min

Two New Immunotherapy Trials Aim to Make Therapy More Effective

Two clinical trials in the Lustgarten Foundation’s Clinical Accelerator are testing different combinations of immunotherapy.