Disease Management
613 articles
My Two-Year Journey with Pancreatic Cancer
When filmmaker Glen Trotiner was diagnosed with pancreatic cancer, he learned a new meaning for “treatment.”
Changing My Life for the Better
Robin Schroeder was an avid runner before her pancreatic neuroendocrine tumor diagnosis. Now she’s back competing in half-marathons.
Fighting Pancreatic Cancer in a Petri Dish
Dr. David Tuveson is growing pancreatic cancer tissue called organoids in the lab, to test which drugs will be most effective against a patient’s tumor.
New Drug Shows Positive Results in Early Trials
A new drug called PEGPH20, which helps chemotherapy drugs reach their target, is showing positive results in an ongoing pancreatic cancer trial.
The Cancer Moonshot
Dr. Elizabeth Jaffee of Johns Hopkins is part of the Cancer Moonshot’s Blue Ribbon Panel, and she explains the goals of the program.
Testing Vitamin C as a Cancer Killer
Lewis Cantley’s team is starting clinical trials of vitamin C to gain more information about its role in stopping cancer.
Synergy with Metronomic Chemotherapy
Oncologists are trying metronomic chemotherapy, lower doses of toxic drugs given on a steady basis, to fight pancreatic cancer.
The Stroma Presents Challenges and Treatment Opportunities
Dr. Elizabeth Jaffee explains how researchers are approaching penetrating the fibrous stroma around pancreatic tumors, which has long challenged treatment.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
A Potential Role for PARP Inhibitors in Pancreatic Cancer
Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.
Tough Tortoise of a Drug Beating Metastatic Pancreatic Cancer
Rexahn Pharmaceuticals is testing RX-3117, a slow-releasing drug similar to gemcitabine, in a clinical trial for metastatic pancreatic cancer patients.
New Study Combines Checkpoint Inhibitors with Radiation Therapy to Boost Immune Response
Dr. Theodore Hong combines checkpoint inhibitors–a type of immunotherapy–with radiation to boost the immune system in pancreatic cancer treatment.
Taking a Systems Biology Approach to Find a New Pancreatic Cancer Target
Dr. Andrea Califano is using systems biology and cell regulators to find new targets in the search for ways to stop pancreatic cancer cells.
Exploiting DNA Mutations For Pancreatic Cancer Treatment
Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.
Challenge Grant Recipients Moving Forward
The Pancreatic Cancer Collective awarded four teams a second round of New Therapies Challenge Grants, to further develop new pancreatic cancer treatment.