Molecular Profiling
186 articles
Pancreatic Cancer Tissue Helps Unlock the Disease’s Secrets
Dr. Christine Iacobuzio-Donahue at Memorial Sloan Kettering is using techniques from evolutionary biology to learn how pancreatic cancer grows.
New Biopsy Shows Promise For Pancreatic Cancer Patients
Trovagene is developing a liquid biopsy for pancreatic cancer patients, to allow doctors to test for cancer and track treatment response.
The Cancer Moonshot
Dr. Elizabeth Jaffee of Johns Hopkins is part of the Cancer Moonshot’s Blue Ribbon Panel, and she explains the goals of the program.
Targeted Therapy for Pancreatic Cancer
Dr. Margaret Tempero outlines the work being done in the area of targeted therapy for pancreatic cancer, specifically the testing of ibrutinib.
New Cancer Stem Cell Pathway Drug May Change Standard of Care
Dr. Tanios Bekaii-Saab is testing a new drug that works on pancreatic cancer stem cells to make chemotherapy more effective.
Collaborative Multi-Center Immunotherapy Trial Targets CD40 and PD-1
Dr. Mark O’Hara outlines a collaborative clinical trial of two immunotherapy agents–a checkpoint inhibitor and a monoclonal antibody–plus standard chemotherapy.
New Research Sheds Light on Hot and Cold Tumors
Dr. Ben Z. Stanger and his team are finding links between the number of T cells a tumor has and the effectiveness of immunotherapy.
Damage as a Way to Repair Pancreatic Cancer
Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.
Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer
Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.
Looking Back at the Year in Research: 2019
Research highlights of 2019 include: approval of a PARP inhibitor, artificial intelligence to diagnose pancreatic cysts, and updated radiation guidelines.
Taking a Systems Biology Approach to Find a New Pancreatic Cancer Target
Dr. Andrea Califano is using systems biology and cell regulators to find new targets in the search for ways to stop pancreatic cancer cells.
Exploiting DNA Mutations For Pancreatic Cancer Treatment
Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.
Targeting Metabolic Vulnerability
Dr. Jordan Winter looks at cell metabolism to find areas of vulnerability in pancreatic cancer cells, to find a way to create better treatments.
AACR Virtual Special Conference on Pancreatic Cancer: Day Two Highlights
Let’s Win and the Lustgarten Foundation present highlights of Day Two of the AACR Virtual Special Conference on Pancreatic Cancer.
Cachexia Research Gaining Momentum
Why do pancreatic cancer patients lose weight even if they are eating well? Dr. Teresa Zimmers explains the syndrome called cachexia.