Genetic Mutations and Family History

38 Articles

Dr. Beatriz Carreno
Research
April 16, 2020 • 5 Min

Targeting Mutant KRAS with Immunotherapy

Dr. Beatriz Carreno explains how her team is targeting the KRAS mutation with a pancreatic cancer vaccine to make the immune system work against cancer.

DNA aqua pipette
Research
February 26, 2020 • 6 Min

Exploiting DNA Mutations For Pancreatic Cancer Treatment

Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.

Dr. Christine Iacobuzio-Donahu
Research
November 12, 2019 • 6 Min

Using Tumor Tissue Samples to Break Down Assumptions About Pancreatic Cancer

Dr. Christine Iacobuzio-Donahue uses tumor tissue samples to study how pancreatic cancer tumors develop, so she can find ways to stop the disease.

Researcher Rene Bernard
Research
October 17, 2019 • 3 Min

Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer

Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.

GENERATE logo
Research
June 24, 2019 • 6 Min

GENERATE Study Aims to Improve Genetic Testing and Prevention for Pancreatic Cancer

Dr. Sapna Syngal outlines the GENERATE study, which aims to help families with a risk for pancreatic cancer by providing genetic testing.

Dr. Talia Golan
Research
March 26, 2019 • 4 Min

Damage as a Way to Repair Pancreatic Cancer

Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.

Gloria Peterson, Ph.D.
Research
February 4, 2019 • 5 Min

Genetic Testing for All Pancreatic Cancer Patients

A study by Dr. Gloria Petersen’s research team has led to an official recommendation that all pancreatic cancer patients get genetic testing.

Old medicine bottles
Research
January 22, 2019 • 4 Min

A PARP Inhibitor Approval for Pancreatic Cancer

PARP inhibitors, a type of targeted therapy, are being studied as treatment for pancreatic cancer in a number of clinical trials.

Dr. Sapna Syngal
Research
November 14, 2018 • 4 Min

New NCCN Guidelines Stress Genetic Testing For All Pancreatic Cancer Patients

Dr. Sapna Syngal discusses the new NCCN guidelines, which support genetic testing for all pancreatic cancer patients, because mutations can influence treatment.

Kim Reiss Binder
Research
November 1, 2018 • 5 Min

PARP Inhibitors for Pancreatic Cancer Maintenance Treatment

Dr. Kim Reiss Binder is leading a clinical trial of maintenance treatment with the PARP inhibitor rucaparib, for patients who carry the BRCA mutation.

Draining board
Research
July 5, 2018 • 4 Min

A Potential Role for PARP Inhibitors in Pancreatic Cancer

Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.

Looking down a spiral staircase
Research
April 5, 2018 • 4 Min

Genetic Testing Can Help Those You Love

Dr. Fay Kastrinos, director of the Muzzi Mirza Pancreatic Cancer Prevention and Genetics Program at Columbia University Medical Center, explains the value of genetic testing for cancer prevention and treatment.

DNA representation
Research
December 5, 2017 • 5 Min

The ABCs of Genetic Testing

There are a number of different genetic mutations that can cause familial pancreatic cancer. This article explains some of the most common ones.

Gloria Peterson, Ph.D.
Research
October 12, 2017 • 5 Min

Tumor Genetics Research Brings Some Answers for Families at High Risk

Professor Gloria Peterson of the Mayo Clinic is working on tumor genetics to help make early detection of pancreatic cancer a reality.

Dr. Robert Kurtz
Research
September 18, 2017 • 4 Min

A Registry for Those at Risk for Pancreatic Cancer

Dr. Robert Kurtz founded the Pancreatic Tumor Registry at Memorial Sloan Kettering to learn more about the genetic mutations that cause pancreatic cancer.