Genetic Mutations and Family History

41 Articles

multicolored abstract DNA against a black background
Research
April 29, 2021 • 3 Min

Chemotherapy Plus Stem Cell Infusion and Vitamins for BRCA Mutated Pancreatic Cancer

A clinical trial for pancreatic cancer patients with a BRCA mutation uses a combination of chemotherapy, vitamins, and stem cells.

Angela Bradbury MD
Research
April 26, 2021 • 5 Min

Improving Access to Genetic Testing and Counseling

Dr. Angela Bradbury is leading a study on access to genetic testing and genetic counseling, including a telehealth option.

Dr. Sapna Syngal
Research
July 2, 2020 • 4 Min

GENERATE Trial Expands Eligibility

Dr. Sapna Syngal explains the expanded eligibility standards for the GENERATE Study for genetic testing of pancreatic cancer patients and relatives.

Dr. Beatriz Carreno
Research
April 16, 2020 • 5 Min

Targeting Mutant KRAS with Immunotherapy

Dr. Beatriz Carreno explains how her team is targeting the KRAS mutation with a pancreatic cancer vaccine to make the immune system work against cancer.

DNA aqua pipette
Research
February 26, 2020 • 6 Min

Exploiting DNA Mutations For Pancreatic Cancer Treatment

Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.

Dr. Christine Iacobuzio-Donahu
Research
November 12, 2019 • 6 Min

Using Tumor Tissue Samples to Break Down Assumptions About Pancreatic Cancer

Dr. Christine Iacobuzio-Donahue uses tumor tissue samples to study how pancreatic cancer tumors develop, so she can find ways to stop the disease.

Researcher Rene Bernard
Research
October 17, 2019 • 3 Min

Dousing Out-of-Control KRAS Signaling in Pancreatic Cancer

Rene Bernards and his team are targeting the signaling pathway of the KRAS mutation, which occurs in almost all pancreatic cancers.

GENERATE logo
Research
June 24, 2019 • 6 Min

GENERATE Study Aims to Improve Genetic Testing and Prevention for Pancreatic Cancer

Dr. Sapna Syngal outlines the GENERATE study, which aims to help families with a risk for pancreatic cancer by providing genetic testing.

Dr. Talia Golan
Research
March 26, 2019 • 4 Min

Damage as a Way to Repair Pancreatic Cancer

Dr. Talia Golan takes a closer look at the damage caused by the BRCA1/2 mutations to find a way to treat pancreatic cancer.

Gloria Peterson, Ph.D.
Research
February 4, 2019 • 5 Min

Genetic Testing for All Pancreatic Cancer Patients

A study by Dr. Gloria Petersen’s research team has led to an official recommendation that all pancreatic cancer patients get genetic testing.

Old medicine bottles
Research
January 22, 2019 • 4 Min

A PARP Inhibitor Approval for Pancreatic Cancer

PARP inhibitors, a type of targeted therapy, are being studied as treatment for pancreatic cancer in a number of clinical trials.

Dr. Sapna Syngal
Research
November 14, 2018 • 4 Min

New NCCN Guidelines Stress Genetic Testing For All Pancreatic Cancer Patients

Genetics impact your treatment for pancreatic cancer. Dr. Sapna Syngal discusses the recommendation of genetic testing for all pancreatic cancer patients.

Kim Reiss Binder
Research
November 1, 2018 • 5 Min

PARP Inhibitors for Pancreatic Cancer Maintenance Treatment

Dr. Kim Reiss Binder is leading a clinical trial of maintenance treatment with the PARP inhibitor rucaparib, for patients who carry the BRCA mutation.

Draining board
Research
July 5, 2018 • 4 Min

A Potential Role for PARP Inhibitors in Pancreatic Cancer

Dr. Michael Pishvaian leads research into the possible role of PARP inhibitors in treating pancreatic cancer patients with certain genetic mutations.

Looking down a spiral staircase
Research
April 5, 2018 • 4 Min

Genetic Testing Can Help Those You Love

Dr. Fay Kastrinos, director of the Muzzi Mirza Pancreatic Cancer Prevention and Genetics Program at Columbia University Medical Center, explains the value of genetic testing for cancer prevention and treatment.